New hope for Hard-to-Treat cancers: enhertu studied in 20+ tumor types
NCT ID NCT07124000
First seen Jun 25, 2026 · Last updated Jul 23, 2026 · Updated 5 times
Summary
This study is testing the drug T-DXd (Enhertu) in 100 adults with advanced HER2-positive solid tumors who have already tried other treatments and have no good options left. The goal is to see how well the drug works in real-world settings, including how many patients respond and for how long. The study covers many cancer types, such as bladder, cervical, ovarian, and pancreatic cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Trastuzumab deruxtecan (Enhertu)
- What this could lead to
- If successful, this could show that T-DXd is an effective treatment option for many types of HER2-positive cancers that have stopped responding to other therapies.
- What could go wrong
- This is an observational study, not a controlled trial, so results may be less definitive. The drug may not work for all tumor types, and side effects like lung inflammation are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Research Site
RECRUITINGBirmingham, Alabama, 35243, United States
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Research Site
RECRUITINGBullhead City, Arizona, 86442, United States
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Research Site
RECRUITINGCasa Grande, Arizona, 85122, United States
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Research Site
RECRUITINGSan Diego, California, 92123, United States
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Research Site
RECRUITINGBoulder, Colorado, 80309, United States
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Research Site
RECRUITINGCoral Springs, Florida, 33065, United States
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Research Site
RECRUITINGSt. Petersburg, Florida, 33714, United States
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Research Site
RECRUITINGWest Palm Beach, Florida, 33401, United States
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Research Site
RECRUITINGDecatur, Illinois, 62526, United States
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Research Site
RECRUITINGTopeka, Kansas, 66604, United States
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Research Site
RECRUITINGFarmington, New Mexico, 87401, United States
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Research Site
RECRUITINGDurham, North Carolina, 27708, United States
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Research Site
RECRUITINGWilson, North Carolina, 27893, United States
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Research Site
RECRUITINGCanton, Ohio, 44718, United States
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Research Site
RECRUITINGMaumee, Ohio, 43537, United States
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Research Site
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Research Site
RECRUITINGNashville, Tennessee, 37203, United States
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Research Site
RECRUITINGDallas, Texas, 75390, United States
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