TESTICULAR CANCER

This is a very early-stage study to test the safety of a new drug called GV20-0251 in adults with advanced solid tumors that have progressed despite standard treatments. The main goal is to find a safe dose by giving the drug to small groups of patients at different levels. It is…

This study is testing whether it is safe to combine a new targeted drug called tarlatamab with standard radiation therapy. It is for adults with advanced cancers that have a specific protein called DLL3, including certain lung cancers, melanoma, and others. The main goal is to se…

This early-stage trial is testing a new drug called CTIM-76 for people with advanced ovarian, testicular, or endometrial cancers that have stopped responding to standard treatments. The study will enroll 80 participants to determine safe dosage levels and see if the drug helps co…

This study aims to see how well the drug T-DXd works in real-world settings for patients with advanced HER2-positive cancers who have already tried other treatments and have no good options left. It will follow about 100 patients with various solid tumors (excluding breast, lung,…

This study is testing if a daily low-dose aspirin pill can prevent dangerous blood clots in men with advanced testicular or germ cell cancer who are receiving chemotherapy. The trial will enroll 35 participants at high risk for clots to take aspirin daily for 6 months while under…

This study is comparing two standard surgical techniques for removing a testicle when cancer is suspected. Researchers want to see if a modified technique that spares a specific muscle layer causes less pain after surgery, reduces the need for opioid painkillers, and leads to few…

This study is testing a digital health program called AYA STEPS that helps young adult cancer survivors manage symptoms like pain, fatigue, and emotional distress. The program teaches skills to improve communication with healthcare providers and engagement with recommended follow…

This study compares two different pain management approaches for men undergoing surgery for testicular cancer. Researchers want to see which method better controls pain while reducing the amount of opioid medication needed after surgery. The study involves 142 male participants a…

This study is testing a new artificial intelligence (AI) tool designed to help match people with advanced cancer to suitable clinical trials. It will enroll up to 50,000 patients to see if using this AI system makes it easier for patients to find and join trials. The researchers …

This study is building a large, long-term database of health information and biological samples from people with cancer, people at risk for cancer, and healthy volunteers. The goal is to collect this data to help researchers better understand what causes cancer and how to prevent…