NASOPHARANGEAL CANCER

This study looks at how well the drug T-DXd works in adults with advanced HER2-positive solid tumors that have spread and are not responding to other treatments. About 100 people will be followed to see if their tumors shrink and how long that lasts. The goal is to provide a trea…

This study tests a new treatment sequence for people with high-risk nasopharyngeal cancer. It compares immunotherapy combined with chemotherapy and radiation followed by maintenance immunotherapy versus standard maintenance with capecitabine. The goal is to see which approach bet…

This study tests whether adding radiation therapy after immunotherapy and chemotherapy can help people with nasopharyngeal cancer that has come back. About 94 adults whose cancer returned at least a year after initial treatment will receive a PD-1 inhibitor plus chemotherapy, the…

This study tests whether waiting to give radiation therapy (salvage) is as effective as giving it right away after a combination of immunotherapy (PD-1 inhibitor) and chemotherapy for people with nasopharyngeal cancer that has spread to other parts of the body. The goal is to see…

This study tests whether adding low-dose radiation to a standard chemotherapy and immunotherapy combination can help control advanced nasopharyngeal cancer that has returned or spread. About 55 adults aged 18-65 with this specific cancer type will receive the treatment. The goal …

This study tests whether a topical chlorhexidine spray can prevent severe skin reactions caused by radiation therapy in people with nasopharyngeal cancer. About 148 participants will receive either the spray or a placebo during their radiation treatment. The goal is to see if the…