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Immunotherapy after Chemo-Radiation shows promise for advanced cervical cancer

NCT ID NCT03833479

Ongoing Disease control Sponsor: Grupo Español de Investigación en Cáncer de Ovario Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the immunotherapy drug TSR-042 can help prevent cervical cancer from returning in patients with high-risk locally advanced disease who have completed standard chemo-radiation. About 134 women will receive TSR-042 as a maintenance therapy to see if it extends the time before the cancer progresses. The approach aims to boost the immune system's ability to fight any remaining cancer cells after radiation.

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Conditions

The condition(s) this trial relates to.

cancer cervical cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADVANCED CANCER CERVICAL CANCER

Contacts and locations

Locations

  • Acibadem Maslak Hospital

    Istanbul, Sarıyer, 34457, Turkey (Türkiye)

  • Ankara City Hospital

    Ankara, Anadolu Bölgesi, 06800, Turkey (Türkiye)

  • Ankara Oncology Training and Research Hospital

    Ankara, Anadolu Bölgesi, 06200, Turkey (Türkiye)

  • Clinica Universitaria de Navarra

    Madrid, Spain

  • H Reina Sofía Cordoba

    Córdoba, 14004, Spain

  • H Vall d'Hebron

    Barcelona, 08035, Spain

  • H. Parc Taulí

    Sabadell, 08208, Spain

  • Hacettepe University

    Ankara, Anadolu Bölgesi, 06800, Turkey (Türkiye)

  • Hospital Clinico Universitario Virgen Arrixaca

    Murcia, Spain

  • Hospital Clínic

    Barcelona, Spain

  • Hospital Clínico San Carlos

    Madrid, Spain

  • Hospital Clínico Universitario de Valencia

    Valencia, Valencia, 46010, Spain

  • Hospital General Universitario de Elche

    Elche, Alicante, Spain

  • Hospital La Fe

    Valencia, Valencia, 46026, Spain

  • Hospital Marqués de Valdecilla

    Santander, Spain

  • Hospital Ramon y Cajal

    Madrid, Spain

  • Hospital Son Espases

    Palma de Mallorca, Spain

  • Hospital Son Llatzer

    Palma de Mallorca, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Madrid, Spain

  • Hospital Universitario Donostia- Donostia Unibertsitate Ospitalea

    Donostia / San Sebastian, Gipuzkoa, 20014, Spain

  • Hospital Universitario La Paz

    Madrid, Madrid, 28046, Spain

  • Hospital Universitario Morales Meseguer

    Murcia, Spain

  • Hospital Universitario Virgen del Rocío

    Seville, Sevilla, Spain

  • Hospital Virgen de la Victoria

    Málaga, Spain

  • Hospital de Terrassa

    Terrassa, Spain

  • Hospital Álvaro Cunqueiro

    Vigo, Pontevedra, Spain

  • ICO Girona

    Girona, Girona, 17007, Spain

  • ICO Hospitalet

    Hospitalet Del Llobregat, Spain

  • Instituto Valenciano de Oncología

    Valencia, Valencia, 46009, Spain

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