CERVICAL CANCER

This study is testing whether new drug combinations work better than standard chemotherapy for advanced cervical cancer that has returned or spread. Researchers will compare LB1410 plus lenvatinib, with or without another drug called LB4330, against chemotherapy chosen by doctors…

This study is testing if adding an experimental drug called telaglenastat (CB-839) to the standard chemoradiation treatment helps people with advanced cervical cancer live longer without their cancer getting worse. It will enroll 42 adults with newly diagnosed, advanced cervical …

This early-stage study is testing whether a new drug called KRC-01, injected directly into the tumor, can make radiation therapy more effective against locally advanced cervical cancer. The trial will first check the safety of different dosing schedules in 10 patients, then compa…

This study is testing an experimental vaccine called PDS0101 in adults living with HIV who also have an HPV 16 infection. The goal is to see if the vaccine is safe and can help the immune system fight the HPV virus, which can cause cervical and anal cancers. All 27 participants w…

This study is testing a shorter, more intensive radiation schedule for women with cervical cancer in Uganda. It compares this new schedule to the standard, longer one to see if it is just as safe and effective at controlling the cancer. The goal is to find a treatment that is eas…

This study is testing whether a new drug called SYS6002 works better than standard chemotherapy for women whose cervical cancer has returned or spread after previous treatments. It will involve about 412 women aged 18-75 whose cancer progressed despite platinum-based chemo and im…

This study is testing a new three-drug combination as a treatment given before surgery for locally advanced cervical cancer. The goal is to see if this combination can completely eliminate the cancer from the removed tissue and is safe for patients. It will involve about 25 parti…

This study compares two standard radiation treatments for cervical and endometrial cancer patients. Researchers want to see which causes fewer digestive side effects like diarrhea. The study will enroll 116 patients who will receive either proton or photon radiation therapy.

This study is creating and testing a patient navigation program to help young adults who have survived cancer. The program aims to guide survivors to get the recommended primary care and cancer check-ups they need. Researchers will first adapt an existing program for young surviv…

This study is testing whether a combination of two drugs, Utidelone and Toripalimab, can help control advanced cervical cancer that has returned or spread after standard chemotherapy. It will involve about 32 patients who have already tried other treatments. The main goals are to…

This study is testing a new type of microscope called DeepDOF. It takes high-quality digital images of cervical tissue samples right after they are collected. The goal is to see if these images can help doctors diagnose cervical cancer and pre-cancer as accurately as standard lab…

This study is testing whether mailing at-home HPV test kits helps more women get screened for cervical cancer. Researchers will enroll 100 women who are overdue for screening and send them self-collection kits. The main goal is to see how many women return the kits and complete f…

This study is testing a training program for doctors and clinics to help more women get screened for cervical cancer and receive proper follow-up care if a test is abnormal. It will involve about 80,000 patients across three different regions in the US. The goal is to prevent cer…

This study is testing a program that uses text messages and at-home test kits to help women living with HIV get screened for cervical cancer. Researchers will first ask healthcare providers for feedback, then pilot the program with about 130 women. The goal is to see if the text-…

This study is testing whether a simple hand and foot exercise program can help reduce nerve pain and improve quality of life for older women receiving chemotherapy for gynecologic cancers. Researchers will enroll 74 participants aged 65+ who are experiencing nerve pain from their…

This study aims to see if a special support program can improve sexual health and overall quality of life for women who have been treated for cervical cancer. It will compare 120 women who receive the new program (including education and specific therapies) to those who receive s…

This study is testing whether starting pelvic floor physical therapy shortly after radiation treatment can help reduce bowel and bladder incontinence in women with cervical cancer. The research will follow 28 patients who receive this specialized therapy four weeks after completi…

This study is testing a blood test to see if it can find tiny traces of cancer left behind after treatment for uterine or cervical cancer. Researchers will follow 600 patients, taking blood samples regularly to check if the test can spot a recurrence earlier than standard scans o…

This study aims to understand why women living with HIV in South Africa, who are at high risk for cervical cancer, sometimes miss important follow-up medical appointments after an abnormal Pap smear. Researchers will interview patients and healthcare providers to identify barrier…

This study is testing a new AI tool designed to help medical teams plan treatment for cervical cancer during pregnancy. It will compare the AI's recommendations against those from real human expert teams and junior doctors. The goal is to see if the AI system can provide accurate…

This study aims to understand if measuring blood flow to tumors using a special 3D ultrasound can help doctors. It will look at women with cervical cancer, precancerous cervical changes, or ovarian cancer. The goal is to see if these blood flow measurements can predict how the di…