Vitamins e and CoQ10 tested as shield against radiation damage
NCT ID NCT07668284
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether taking high doses of vitamin E and CoQ10 daily for 90 days can reduce chronic side effects from pelvic radiation in people treated for prostate, uterine, cervical, or anal cancer. Researchers will monitor safety, side effects, and quality of life in 200 adults over about two years. The goal is to find a well-tolerated way to ease long-term radiation toxicity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Coenzyme Q10 (ubidecarenone) and Vitamin E (dl-α-tocopherol acetate) taken daily by mouth for 90 days
- What this could lead to
- If it works, this could offer a simple, low-cost way to ease long-term side effects of pelvic radiation, improving quality of life for cancer survivors.
- What could go wrong
- This is an early-phase trial (Phase 1/2) with only 200 participants, so results may not apply broadly. High-dose vitamins can have side effects, and the study is not designed to prove they improve cancer outcomes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Nebraska Medical Center
Omaha, Nebraska, 68198, United States
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