University Of Nebraska

This study is testing a new, gentle leg movement therapy for people with peripheral artery disease (PAD), a condition that reduces blood flow to the legs. Researchers want to see if moving the legs passively (without muscle effort) during long periods of sitting can improve blood…

This small pilot study is testing if adding a specific prebiotic fiber to food can improve gut health for people with multiple myeloma or lymphoma undergoing a stem cell transplant. Researchers believe a healthier gut might lead to better recovery and survival. About 30 participa…

This early-stage study is testing if a single dose of an existing drug, diroximel fumarate (Vumerity), can help people with peripheral artery disease (PAD) walk better. Researchers believe the drug may reduce harmful stress in blood vessels, improving blood flow to the legs. Abou…

This study is for older adults getting a stem cell transplant for blood cancers. It compares two different doses of a key drug (cyclophosphamide) used to prevent a serious complication called graft-versus-host disease (GVHD). The main goal is to see if a lower dose helps patients…

This study is testing a shorter, combined radiation treatment for men with aggressive prostate cancer that hasn't spread. Researchers want to see if using two targeted radiation methods together can effectively control the cancer while causing fewer side effects. The trial will e…

This study is testing a new, non-invasive device that uses finger and toe sensors to detect poor blood flow in the legs, known as Peripheral Artery Disease (PAD). Researchers want to see if this method, which measures pulse timing, is as good as the current standard test (the ank…

This study aims to find easier and less painful ways to test for respiratory viruses like COVID-19 and the flu. Researchers are comparing a gentle nasal saline wash and a saliva-collecting capsule to the standard, often uncomfortable, deep nose swab. They will enroll 1,000 adults…

This study aims to increase colorectal cancer screening among African American adults aged 45-75, a group that faces higher rates of the disease. Researchers are partnering with a local DMV to offer free, at-home screening kits and support. They will test if adding a social media…

This study is testing a device called the Lung Master to see if it can help people with breathing problems like COPD or asthma. Participants will use the device at home daily for a month to see if it strengthens their breathing muscles and improves lung capacity. The study involv…

This study is testing whether a safe, non-invasive brain stimulation technique can improve memory. It involves healthy young adults, healthy older adults, and older adults with mild memory problems. Researchers will use a device called TMS to stimulate a specific brain area and m…

This study is testing whether meeting with an exercise coach—either in person or by video call—helps adults with a specific type of heart failure (HFpEF) exercise more consistently. Over 18 months, 300 participants will be assigned to one of three groups: one with in-person coach…

This study is testing if a device that sends electrical pulses to the spinal cord can help reduce leg pain in people who have both painful diabetic nerve damage and poor blood circulation. Up to 15 participants who already have the device implanted will try two weeks of real stim…

This study is testing a smartphone app called 'Family Room' designed to help family members caring for a loved one in the Intensive Care Unit (ICU). Researchers want to see if using the app improves caregivers' well-being, reduces their stress, and helps them feel more engaged an…

This study is testing whether a dietary supplement called MitoQ, taken daily for six months, can help people with peripheral artery disease (PAD) who get leg pain when walking. Researchers want to see if MitoQ helps participants walk farther, be more active, feel better, and impr…

This study aims to help caregivers of adolescents with profound autism get short breaks from constant supervision. Caregivers will be trained to use picture-based activity schedules to help their child engage in tasks independently for longer periods. Researchers will test if thi…

This study is testing whether a daily nasal spray containing oxytocin, a natural hormone, can help reduce chronic stress and improve quality of life for women who are family caregivers for someone with dementia. Researchers will enroll 32 female caregivers to receive either a low…

This study is testing if a simple, at-home heat therapy for the legs can help people with long COVID feel better and move more easily. Researchers want to see if warming the legs for about 45 minutes, several times a week, is safe and can improve walking distance, reduce fatigue,…

This study aims to understand if chronic stress is linked to gut bacteria and whether six weeks of group therapy can change them. Researchers will enroll 30 women who will attend weekly therapy sessions and provide stool samples before and after. The goal is to gather knowledge a…

This study aims to understand how deep brain stimulation (DBS) treatment affects attention, eye movement, and emotion perception in people with Parkinson's disease and essential tremor. Researchers will track eye movements while participants view facial expressions before, during…

This study aims to understand the real-world experience of providing and receiving long-acting HIV injections for people who live far from their main HIV clinic. Researchers will work with about 55 patients and clinic staff in Nebraska and Iowa to identify the main barriers—like …

This study aims to find early warning signs of pancreatic cancer by tracking people at higher risk. Researchers will collect health information and blood samples from 1250 participants over time. The goal is to spot patterns that could lead to earlier detection and better surviva…

This study aims to understand how using a 3D-printed prosthetic arm affects brain activity and movement in children born with a limb difference. Researchers will measure brain signals and motor skills in 40 children, some with limb differences and some without, while they perform…

This study aims to understand how existing gum inflammation affects the body's natural healing process after a tooth is removed. Researchers will recruit 25 adults who need a back tooth extracted. They will take small tissue samples from the extraction site right after the tooth …

This study is building a large, long-term database of health information and biological samples from people with cancer, people at risk for cancer, and healthy volunteers. The goal is to collect this data to help researchers better understand what causes cancer and how to prevent…

This study aims to learn more about how gums heal after a tooth is pulled, especially in older adults. Researchers will enroll 12 people needing a back tooth removed. Half will receive a gel made from their own blood (platelet-rich fibrinogen) placed in the empty socket. The stud…

This study aims to find the best way to help intensive care unit (ICU) teams consistently use a proven set of care practices known as the ABCDEF bundle. Researchers will test two different support strategies for hospital staff across 12 ICUs, involving about 8,100 critically ill …

This study aims to understand how the brain reorganizes its critical functions, like movement and speech, after surgery to remove a tumor. Researchers will use advanced brain scans and tests before surgery, during the operation, and again at 2 and 6 months after to track these ch…