Could tailored brain stimulation quiet Parkinson's tremors more effectively?
NCT ID NCT04799470
First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time
Summary
This pilot study is testing whether personalized deep brain stimulation (DBS) patterns can better control Parkinson's motor symptoms while causing fewer side effects than standard settings. Researchers will enroll 10 people already implanted with the Medtronic Percept PC DBS device and compare their usual stimulation with new, patient-tailored patterns. The goal is to see if targeting excessive brain synchrony more precisely leads to smoother movement and less discomfort.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- novel deep brain stimulation patterns delivered via the Medtronic Percept PC device
- What this could lead to
- If successful, this could point toward more effective and personalized DBS therapy for Parkinson's disease with fewer side effects.
- What could go wrong
- This is a very small, early feasibility pilot with only 10 participants, so results may not apply broadly. The novel patterns may not work better than standard stimulation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Unversity of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68118, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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