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Could a gentle leg wiggle protect your arteries while you sit?

NCT ID NCT06389149

Recruiting now Knowledge-focused Sponsor: University of Nebraska Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a simple, passive leg movement called LEAP therapy in people with peripheral artery disease (PAD). Participants sit for 2.5 hours with or without the leg movement, and researchers measure blood flow, walking ability, and other health markers. The goal is to see if this easy motion can counteract the harmful effects of prolonged sitting on leg circulation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
LEAP therapy (passive leg movement)
What this could lead to
If it works, this could point toward a simple way to protect leg blood flow during long periods of sitting for people with peripheral artery disease.
What could go wrong
This is a very small, early-stage study (24 participants) testing a short-term effect, not a treatment. It may not lead to any lasting benefit or change in clinical practice.

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Conditions

The condition(s) this trial relates to.

peripheral arterial disease peripheral arterial occlusive disease 1 peripheral vascular disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIPHERAL ARTERIAL DISEASE PERIPHERAL ARTERY DISEASE PERIPHERAL ARTERY OCCLUSIVE DISEASE PERIPHERAL VASCULAR DISEASE

Contacts and locations

Locations

  • University of Nebraska - Omaha

    RECRUITING

    Omaha, Nebraska, 68182, United States

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