Peripheral arterial occlusive disease 1

This study tests a new drug called APAC, which is designed to prevent blood clots in people with blocked leg arteries. The trial includes 42 adults with peripheral arterial disease or chronic limb-threatening ischemia. Researchers will check if APAC is safe and well-tolerated, an…

This early-phase trial tests whether a single dose of Vumerity (diroximel fumarate) can improve blood vessel function and walking ability in 20 people aged 50-75 with peripheral artery disease (PAD). Participants will receive either Vumerity or a placebo, and researchers will mea…

This study looks at how often sleep apnea occurs in people with peripheral artery disease (blocked leg arteries). Researchers will monitor 295 adults with leg artery disease using a sleep test. The goal is to better understand the connection between these two conditions, which ma…

This observational study will follow 2000 adults with type 2 diabetes to see how their eating habits, body composition, and grip strength change over time. Researchers hope to identify patterns that could help improve care. Participants must be 18 or older and able to complete ba…

This study tests a simple, passive leg movement called LEAP therapy in people with peripheral artery disease (PAD). Participants sit for 2.5 hours with or without the leg movement, and researchers measure blood flow, walking ability, and other health markers. The goal is to see i…