Brain cancer fog: could a common antidepressant boost thinking?

NCT ID NCT03728673

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether escitalopram, a common antidepressant, can improve thinking and memory problems in people with a severe type of brain tumor called grade IV glioma. Up to 85% of these patients struggle with cognitive issues from the tumor or its treatment. The study will give 20 participants the drug for 17 weeks and measure changes in cognition, mood, and quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain glioma glioblastoma glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Nebraska Medical Center

    RECRUITING

    Omaha, Nebraska, 68198, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••