Brain cancer fog: antidepressant may sharpen thinking in glioma patients

NCT ID NCT03728673

First seen Apr 29, 2026 · Last updated May 14, 2026 · Updated 4 times

Summary

This study tests whether the antidepressant escitalopram can improve memory, focus, and overall thinking in people newly diagnosed with a fast-growing brain cancer (grade IV glioma). About 20 participants will take the drug for 17 weeks and complete thinking and mood tests. The goal is to see if the drug can ease cognitive side effects from the tumor and its treatments like radiation and chemotherapy.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Nebraska Medical Center

    RECRUITING

    Omaha, Nebraska, 68198, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.