University Of Nebraska
Clinical trials sponsored by University Of Nebraska, explained in plain language.
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Scientists hunt for clues in Parkinson's blood after Year-Long drug trial
Disease control CompletedThis study tested the safety of a 48-week treatment with a drug called Leukine (sargramostim) in 11 people with Parkinson's disease. Researchers closely monitored participants for side effects and collected blood samples to look for biological changes, or 'biomarkers,' that might…
Phase: PHASE1 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Apr 01, 2026 21:26 UTC
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Three-Year Parkinson's drug test seeks to calm overactive immune system
Disease control CompletedThis small, early-stage study tested the safety of giving a drug called Leukine to people with Parkinson's disease for three years. Researchers wanted to see if this drug, which affects the immune system, was safe and tolerable at a lower dose schedule. They also checked if the t…
Phase: PHASE1 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Could a simple vitamin help fight blood cancers?
Disease control CompletedThis study tested whether giving vitamin D supplements to patients with newly diagnosed lymphoma or leukemia who have low vitamin D levels could help control their cancer. Researchers compared high-dose and low-dose vitamin D against no treatment to see if it improved how long pa…
Phase: NA • Sponsor: University of Nebraska • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Can cash and media smarts help young adults kick the vape habit?
Disease control CompletedThis small pilot study tested different ways to help young adults quit vaping. It compared a standard text-message support program to versions that added media literacy lessons, financial rewards, or both. The goal was to see which approach was most practical and showed the most …
Phase: NA • Sponsor: University of Nebraska • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New program aims to support black moms and manage pregnancy blood pressure
Disease control CompletedThis study tested a new support program called PARITY for pregnant Black women. The program combined a community doula, helpful resources, and a mobile app with positive messages to promote healthy habits. Researchers wanted to see if the program was practical to run and if it he…
Phase: NA • Sponsor: University of Nebraska • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New pill aims to stop leukemia from coming back after transplant
Disease control CompletedThis early-stage study tested whether a weekly pill called ONC-201 could safely help prevent leukemia or MDS from returning after a stem cell transplant. It involved 20 patients who had recently received a transplant and took the pill for up to one year. The main goal was to chec…
Phase: PHASE1 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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Three-drug combo tested to stop early breast cancer from coming back
Disease control CompletedThis study tested a combination of three drugs given after surgery for early-stage HER2-positive breast cancer. The goal was to see if this treatment could help prevent the cancer from returning and to understand its side effects. It involved 20 patients who received the drug reg…
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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Tailored treatment tested to boost survival for older leukemia patients
Disease control CompletedThis study tested a personalized approach to treat acute myeloid leukemia (AML) in adults aged 60 and older. Doctors assigned patients to either strong or milder chemotherapy based on their genetic risk and a detailed health assessment. The goal was to see if this tailored strate…
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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Pig vs. cow collagen: which heals your jaw better?
Disease control CompletedThis study compared two different collagen materials—one from pigs and one from cows—used to cover a bone graft after a tooth is pulled. The goal was to see which one helps the gum tissue and new bone heal better in preparation for a future dental implant. Researchers measured ti…
Phase: NA • Sponsor: University of Nebraska • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Finger prick could replace urine for pregnancy tests
Diagnosis CompletedThis study tested if a simple finger-prick blood sample could be used for a rapid pregnancy test. Researchers wanted to see if this method works as well as standard urine tests, especially in situations where getting a urine sample is difficult or would cause a delay, like in wil…
Sponsor: University of Nebraska • Aim: Diagnosis
Last updated Mar 30, 2026 14:34 UTC
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New tool aims to help women get healthier before pregnancy
Prevention CompletedThis study tested a new, quicker screening tool designed to help women of childbearing age identify health risks and get advice *before* they become pregnant. Researchers compared this new tool, where women choose topics they want to learn about, to a standard, longer screening q…
Phase: NA • Sponsor: University of Nebraska • Aim: Prevention
Last updated Mar 30, 2026 14:30 UTC
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Can a video Game-Like rehab stop arthritis after a torn ACL?
Prevention CompletedThis study tested a new rehabilitation method for people who have recently had ACL knee surgery. It used visual feedback on a screen to help patients relearn how to squat and move more evenly, putting healthy weight on the injured knee. The goal was to see if this early training …
Phase: NA • Sponsor: University of Nebraska • Aim: Prevention
Last updated Mar 30, 2026 14:28 UTC
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Phone app aims to bridge mental health gap for trauma survivors
Symptom relief CompletedThis study tested a self-help smartphone app called BounceBack Now, designed to help people manage symptoms of PTSD, depression, anxiety, and sleep problems. Researchers worked with 29 participants, focusing on underserved groups, to see if using the app in a primary care clinic …
Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Robotic seal cuddles its way into Kids' hospital hearts
Symptom relief CompletedThis study tested if using a robotic baby harp seal named Paro during physical and occupational therapy could help hospitalized children. Researchers wanted to see if the robot made therapy sessions easier and more enjoyable by reducing kids' anxiety and improving their mood. The…
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Pressurized oxygen tested to ease agony of sickle cell crisis
Symptom relief CompletedThis study explored whether a treatment called hyperbaric oxygen therapy could help adults during a sickle cell pain crisis. Eight participants received 1-3 sessions of breathing pure oxygen in a special pressurized chamber. Researchers measured if this reduced their pain and hel…
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Mar 23, 2026 15:16 UTC
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Simple home exercises could ease debilitating fatigue for lung cancer patients
Symptom relief CompletedThis study tested a home-based exercise program designed to help people manage severe fatigue after lung cancer surgery. Researchers worked with 235 patients who had non-small cell lung cancer to see if starting exercises right after surgery or waiting 6 weeks worked better. The …
Phase: NA • Sponsor: University of Nebraska • Aim: Symptom relief
Last updated Mar 19, 2026 14:55 UTC
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Scientists track brain changes after Life-Saving transplants
Knowledge-focused CompletedThis study aimed to understand how stem cell transplants affect thinking, memory, and daily life in adults aged 60 and older. Researchers followed 110 participants with blood cancers, measuring their cognitive function, physical abilities, and quality of life at multiple time poi…
Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC