University Of Nebraska

This early-phase study tested whether a drug called Leukine (Sargramostim) is safe for people with Parkinson's disease when taken for 36 months. Seven participants received a weight-based dose 5 days a week, with 2-day breaks. Researchers monitored side effects, immune system cha…

This study looked at whether tailoring chemotherapy for older adults (60+) with acute myeloid leukemia (AML) based on their genetic profile and overall health can improve outcomes. 75 participants received either standard intensive or milder therapy based on these factors. The go…

This study tested a new oral drug, ADX-629, in 8 people with Sjögren-Larsson syndrome, a rare inherited disorder that causes lifelong skin, brain, and eye problems due to buildup of harmful fatty aldehydes. The goal was to see if the drug is safe and can reduce these harmful subs…

This study tested a program called PARITY that gives pregnant Black women community-based doula support, resources, and a mobile app with positive messages and wellness tips. The goal was to see if the program is practical and helpful for managing blood pressure. About 60 women t…

This study tested a combination of chemotherapy drugs (cyclophosphamide and paclitaxel) plus the targeted therapy trastuzumab given after surgery to 20 patients with early-stage HER2-positive breast cancer. The goal was to see how safe and effective this treatment is at preventin…

This early-phase study tested a drug called ONC-201 in 20 people with high-risk acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who had recently received a stem cell transplant. The goal was to see if taking ONC-201 weekly for a year could help prevent the cancer f…

This study checked if a tiny drop of blood from a finger prick can be used to test for pregnancy, instead of the usual urine test. Thirty pregnant women provided a finger stick blood sample, which was tested with a rapid point-of-care device. The goal was to see if the results we…

This small early study tested a new way to treat microstomia (mouth tightening) caused by scleroderma. Three adults received three sessions of a laser followed by hyaluronidase enzyme application to loosen the skin around the mouth. The goal was to increase mouth opening for easi…

This study tested a breathing technique called Holotropic Breathwork (HB) to see if it could help people recovering from addiction. 25 adults in treatment or living in the community took part in group breathing sessions. The goal was to see if this approach was practical and coul…

This study looked at whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can help adults with sickle cell disease who are having a painful crisis. Eight adults received 1-3 sessions, each about two hours long. Researchers measured pain levels before…

This study looked at whether a home-based exercise program can help people with non-small cell lung cancer manage severe tiredness after surgery. 235 adults took part. The program was designed to be simple, safe, and low-cost. The goal was to reduce fatigue and improve quality of…

This study tested a program that combines media literacy education, text message support, and financial rewards to help young adults (ages 19-29) stop vaping. Forty participants who vaped and wanted to quit were enrolled. The goal was to see if the program was practical and if ad…

This study tested whether using a robotic baby harp seal named Paro during physical and occupational therapy could help hospitalized children. Researchers wanted to see if the robot made therapy sessions easier and more enjoyable for kids aged 5-18, while also reducing their anxi…

This early-phase study tested a drug called sargramostim (Leukine) in 11 people with Parkinson's disease to see if it is safe and to find biological markers (biomarkers) in immune cells that could show how the drug works. Participants received the drug weekly for 48 weeks and had…

This study compared two collagen wound dressings (one from pigs, one from cows) placed over bone graft material after tooth extraction. Nineteen non-smoking adults aged 19-65 who needed a premolar or front tooth pulled took part. The goal was to see if one dressing led to thicker…

This study tested a new exercise program using visual feedback to help people load their knee properly after ACL surgery. The goal was to see if this could prevent knee arthritis, which often develops within 15 years after an ACL injury. 34 participants were followed for 6 months…

This study looked at whether virtual reality can help stroke survivors who walk unevenly (taking longer steps with one leg). Researchers had 42 participants practice walking tasks in a virtual reality setup. They also tested if survivors could accurately feel how uneven their wal…

This study tested a new screening tool that lets women choose which preconception health topics to discuss during routine clinic visits. Researchers wanted to see if this approach helps more women identify risks and feel motivated to make healthy changes. The study involved 286 w…

This study looked at how stem cell transplants affect thinking, memory, and daily life in adults aged 60 to 85 with blood cancer. Researchers measured cognitive function, physical function, and quality of life at several time points. The goal was to understand what factors, like …

This study looked at whether a blood test can measure the death of insulin-making cells in people with cystic fibrosis. Researchers compared levels of a specific DNA marker in 40 participants with cystic fibrosis and healthy controls. The goal was to understand how beta cell deat…

This study tested a mobile app called BounceBack Now that offers self-help for PTSD, depression, sleep problems, and anxiety. Researchers worked with 29 adults in primary care, including many from underserved communities, to see if the app was easy to use and helpful. The goal wa…