New drug aims to keep leukemia at bay after transplant

NCT ID NCT03932643

First seen Nov 06, 2025 · Last updated Apr 28, 2026 · Updated 25 times

Summary

This early-phase trial tested a drug called ONC-201 in 20 people with high-risk acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) who had recently received a stem cell transplant. The goal was to see if taking ONC-201 weekly for a year could help prevent the cancer from coming back. The study focused on safety and side effects, not on curing the disease.

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Contacts and locations

Locations

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.