University Of Nebraska

This study tested whether giving chemotherapy (paclitaxel and cyclophosphamide) with or without the targeted drug trastuzumab before surgery helps shrink breast cancer tumors in 92 women with early-stage or locally advanced breast cancer. The goal was to see if the treatment redu…

This study tests two treatments—isotretinoin (an acne medication) and hCG (a hormone therapy)—to see which better helps men with low or no sperm count produce moving sperm. About 100 men aged 19 to 50 will take one treatment for three months. The goal is to find new options for m…

This early-phase study looks at whether giving low-dose radiation before CAR T-cell therapy is practical and safe for people with B-cell lymphoma that has come back or not responded to treatment. About 33 adults will receive radiation to bridge them to a CAR T-cell infusion. The …

This study tests whether giving a targeted drug (palbociclib) along with hormone therapy before surgery can shrink tumors in people with early-stage hormone receptor-positive, HER2-negative breast cancer. About 51 participants will receive the combination for several weeks before…

This early-stage study tests whether a carefully guided psilocybin (magic mushroom) session can help reduce depression and anxiety in people with advanced, incurable gastrointestinal cancers. The study enrolls 24 adults aged 19-85 who live near Omaha, NE, and have a family member…

This study tests a new drug called BMX-001 added to standard radiation and chemotherapy for people newly diagnosed with anal cancer. The goal is to see if BMX-001 can reduce severe side effects like rectal bleeding and skin damage while still fighting the cancer. About 24 adults …

This study looks at whether a two-week camp using virtual reality (VR) games can improve how children with hemiplegic cerebral palsy use their affected hand and arm. Seventeen children will either play VR games designed to train both hands together or do standard hand-arm trainin…

This study aimed to test the drug ONC201 in people with a type of brain tumor called meningioma that had come back or wasn't responding to other treatments. It planned to measure how much drug gets into the tumor during surgery and how long patients lived without their tumor gett…

This study looks at how well a long-acting HIV injection (CAB+RPV LA) works for people who live far from their doctor. About 55 patients and their clinic staff will share their experiences through surveys and interviews over 15 months. The goal is to understand what helps or make…

This study aimed to understand how the sounds people make while walking help them stay stable. Researchers planned to have healthy adults walk on a treadmill while listening to altered versions of their own footsteps. The study was withdrawn before any participants were enrolled,…

This study tracks how patients store and dispose of opioid pain pills after knee or hip replacement surgery. About 163 adults will learn proper storage and disposal methods, then report what they did with unused pills 6-8 weeks later. The goal is to understand how to reduce lefto…

This study compares new, less invasive ways to collect samples for detecting respiratory viruses like COVID-19. Instead of the standard deep nose swab, researchers are testing a nasal wash, saliva drool, and a special saliva cup. About 1,000 emergency room patients will provide s…

This study looks at whether continuous glucose monitors (CGMs) can help underserved adults with type 2 diabetes better manage their blood sugar. About 50 people with high A1c levels will use a CGM for 6 months, and researchers will track changes in blood sugar control and any pro…

This study looks at how different types of chronic ankle instability affect brain activity and movement control. Researchers will test 42 physically active adults to find differences between those with mechanical looseness, perceived instability, or both. The goal is to create be…