University Of Nebraska

This study is testing whether adding a drug called palbociclib to standard hormone therapy can better shrink tumors before surgery in people with early-stage, hormone-positive breast cancer. It involves 51 participants and aims to see if this combination improves treatment respon…

This study is testing a new drug called BMX-001, given alongside the standard treatment of radiation and chemotherapy for newly diagnosed anal cancer. The main goal is to see if BMX-001 can protect healthy tissues from damage, reducing severe side effects like skin burns, rectal …

This study is testing if adding a low dose of radiation therapy is safe and practical for patients before they receive a CAR-T cell treatment for B-cell lymphoma that has returned or not responded to other therapies. The goal is to see if this combination can improve outcomes for…

This study aimed to learn about a drug called ONC201 for people with a type of brain tumor (meningioma) that had come back or stopped responding to other treatments. It planned to test the drug in two groups: people scheduled for surgery and people with no other treatment options…

This study aims to see if continuous glucose monitors (CGMs) help low-income and uninsured adults with type 2 diabetes manage their condition better than traditional finger-prick meters. Researchers will enroll 50 patients with high blood sugar levels and follow them for six mont…

This study tested a treatment plan for people with early-stage breast cancer who had not yet had surgery. The goal was to see if giving strong chemotherapy before surgery, with or without the drug trastuzumab (Herceptin), could shrink tumors effectively and be well-tolerated. Res…

This early-stage study is testing whether adding a short, focused course of radiation (a 'boost') to a standard immunotherapy drug (durvalumab) is safe and can help control stage III non-small cell lung cancer. The treatment is given after patients finish their initial chemo-radi…

This early-stage study is testing whether a new oral medication called ADX-629 is safe and can reduce the buildup of harmful chemicals in people with Sjögren-Larsson syndrome (SLS), a rare genetic disorder. Up to 8 participants with SLS will take the drug for 12 weeks. Researcher…

This study is testing whether giving patients a special bag and instructions helps them safely destroy leftover opioid pain pills after hip or knee replacement surgery. Researchers want to see if this approach prevents unused pills from being stored or misused at home. About 163 …

This small, early-stage study is exploring whether a guided therapy session using psilocybin (the active compound in 'magic mushrooms') can help reduce severe depression, anxiety, and emotional distress in people with advanced pancreatic, bile duct, or other gastrointestinal canc…

This study is testing whether playing virtual reality (VR) games can help improve hand and arm function in children with hemiplegic cerebral palsy. Children in the study attend a two-week summer camp where they either play special VR games designed for therapy or do standard hand…

This study is testing a guided breathing technique called Holotropic Breathwork to see if it can help people recovering from drug or alcohol addiction. It involves 100 adults who have had a substance use problem in the last five years. The research compares the breathing sessions…

This study aimed to understand if the sounds people make while walking help them walk more steadily. Researchers planned to test healthy young adults by changing or blocking the sounds of their footsteps to see if it affected their walking patterns. The trial was withdrawn before…

This study aims to understand why some people with chronic ankle instability don't recover well from standard rehab. Researchers will measure brain activity and balance in 42 people with different types of ankle instability during physical tests. The goal is to gather information…