Magic mushroom compound tested for cancer anxiety

NCT ID NCT05220046

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tests whether a single dose of psilocybin, the active ingredient in magic mushrooms, can reduce depression and anxiety in people with advanced pancreatic, biliary, or other gastrointestinal cancers. The study enrolls 24 adults aged 19-85 with stage IV or inoperable cancer who live near Omaha, NE. Participants receive the drug in a supportive setting, and researchers track changes in mood and distress over time.

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Conditions

The condition(s) this trial relates to.

biliary tract cancer Biliary Tract Neoplasms digestive system cancer digestive system carcinoma digestive system neoplasm malignant pancreatic neoplasm pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States