New combo therapy shows promise in preventing breast cancer return

NCT ID NCT02654119

First seen Jan 07, 2026 · Last updated May 01, 2026 · Updated 18 times

Summary

This study tested a combination of two chemotherapy drugs (cyclophosphamide and paclitaxel) plus the targeted therapy trastuzumab given after surgery to 20 patients with early-stage HER2-positive breast cancer. The goal was to see if this regimen is safe and effective at preventing the cancer from coming back. The treatment aims to kill any remaining cancer cells and block their growth.

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Contacts and locations

Locations

  • Faith Regional Health Services Carson Cancer Center

    Norfolk, Nebraska, 68701, United States

  • Nebraska Medicine-Village Pointe

    Omaha, Nebraska, 68118, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.