A simple blood draw could reveal hidden brain injury in kids
NCT ID NCT06940232
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This study tests whether two proteins in the blood, GFAP and UCH-L1, can help identify children with traumatic brain injury after a head injury. Researchers will compare blood levels of these proteins in children with different severities of head injury and check whether they match CT scan results and recovery over 3 to 6 months. The goal is to see if a quick blood test could reduce the need for CT scans in children.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Blood test measuring two proteins (GFAP and UCH-L1) after head injury
- What this could lead to
- If it works, a quick blood test could help doctors decide which children need a CT scan after a head injury, reducing unnecessary scans and radiation exposure.
- What could go wrong
- This is an early-stage diagnostic study, and the biomarkers may not reliably predict CT findings or long-term outcomes in children. Results will need confirmation in larger, diverse groups.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Children's Nebraska
RECRUITINGOmaha, Nebraska, 68114, United States
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