Could a simple supplement ease leg pain and help PAD patients walk farther?

NCT ID NCT06409949

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether taking MitoQ for six months can improve walking ability and quality of life in people with peripheral artery disease who experience leg pain while walking. Researchers will measure treadmill walking distance, daily step counts, and leg muscle health in 60 participants. Half will receive MitoQ and half a placebo, with results compared after six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MitoQ (a dietary supplement that targets mitochondria)

What this could lead to

If it works, this could point toward a simple supplement to help people with PAD walk farther and feel better day-to-day.

What could go wrong

This is an early-stage trial with only 60 people, so results may not apply widely. MitoQ is a supplement, not a proven drug, and may show no benefit over placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

peripheral arterial disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • VA Medical Center

    RECRUITING

    Omaha, Nebraska, 68105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••