Zapping the brain to sharpen memory: new trial tests TMS in older adults

NCT ID NCT03574207

Recruiting now Symptom relief Sponsor: University of Nebraska Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can improve memory in healthy adults and in older adults with amnestic mild cognitive impairment (aMCI), a condition that often leads to Alzheimer's. Researchers will use face-word association tasks and brain scans to measure changes. The study enrolls 48 participants across three groups: young adults, healthy older adults, and those with aMCI.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial magnetic stimulation (TMS)
What this could lead to: If it works, this could point toward a non-invasive treatment to improve memory in people with mild cognitive impairment.
What could go wrong: This is a small, early pilot study. Results may not generalize, and memory improvements may be modest or not lasting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Memory Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MEMORY LOSS MILD COGNITIVE IMPAIRMENT

Contacts and locations

Locations

University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States

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