MEMORY LOSS

This study tests whether 6 months of supervised aerobic exercise can improve fitness, brain health, and memory in adults aged 65 and older with mild cognitive impairment or early Alzheimer's disease. Participants will exercise, undergo memory tests, and have MRI scans over a year…

This pilot study tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can improve memory in healthy adults and in older adults with amnestic mild cognitive impairment (aMCI), a condition that often leads to Alzheimer's. Researche…

This study tests whether a gentle electrical current applied to the brain, guided by a caregiver at home, can improve memory, thinking, and walking in older adults with mild cognitive impairment or mild dementia. 144 participants will receive either real or sham stimulation over …

This study aims to find genetic factors that increase the risk of developing dementia before age 70. Researchers will analyze DNA from 1,000 participants, including people with memory concerns or dementia and their healthy family members. The goal is to better understand how gene…

This study is creating a large database of blood tests, digital assessments (like smartphone tasks), and brain scans from 1,200 older adults. Participants may have normal memory, mild memory problems, or mild-to-moderate Alzheimer's. The goal is to see if simple, non-invasive tes…

This early-phase study investigates how scopolamine, a drug known to affect memory, changes brain activity in people with epilepsy who are already undergoing brain monitoring for seizures. Sixty participants will receive either scopolamine or a placebo and perform memory tasks wh…