New combo aims to tackle aggressive brain tumors that have come back
NCT ID NCT05698524
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a new two-drug combination for adults whose high-grade glioma (a fast-growing brain tumor) has returned after standard treatment. The drugs are temozolomide (a chemotherapy pill given daily at low doses) and abexinostat (an experimental drug that may help the chemo work better). The main goals are to find the safest dose and to track side effects in 24 participants.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68198, United States
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