GLIOSARCOMA
Clinical trials for GLIOSARCOMA explained in plain language.
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Sound waves unlock Brain's defenses against deadly tumor
Disease control Recruiting nowThis study tests a new approach for people with a recently diagnosed aggressive brain cancer called glioblastoma. A device with 9 ultrasound emitters is implanted in the skull to temporarily open the blood-brain barrier, allowing immune-boosting drugs to reach the tumor more effe…
Matched conditions: GLIOSARCOMA
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated May 16, 2026 22:33 UTC
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New hope for aggressive brain cancer: drug combo trial opens
Disease control Recruiting nowThis early-stage trial tests a new drug called Peposertib, combined with radiation and chemotherapy, for people with a fast-growing brain cancer (glioblastoma) that has a specific genetic marker (MGMT unmethylated). The goal is to find the best dose and see if the drug can reach …
Matched conditions: GLIOSARCOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Brain tumor trial combines virus and immunotherapy to fight glioblastoma
Disease control Recruiting nowThis study tests a new treatment for people with aggressive brain tumors like glioblastoma. It combines a genetically modified virus (M032) that attacks tumor cells and boosts the immune system, with the immunotherapy drug pembrolizumab. The goal is to see if this combination is …
Matched conditions: GLIOSARCOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New combo aims to fight aggressive brain tumors that have come back
Disease control Recruiting nowThis early-phase study tests a new two-drug combination for adults whose high-grade glioma (a fast-growing brain tumor) has returned after standard treatments. The drugs are temozolomide (given in low, frequent doses) and abexinostat (an experimental pill). The main goal is to fi…
Matched conditions: GLIOSARCOMA
Phase: PHASE1 • Sponsor: University of Nebraska • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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New combo therapy targets deadly brain cancer in early trial
Disease control Recruiting nowThis early-stage study tests whether two experimental drugs, ABBV-637 and ABBV-155, are safe when given alone or with another drug called ERAS-801 for people whose glioblastoma has come back. About 60 adults with a specific type of brain tumor (EGFR gene amplified) will take part…
Matched conditions: GLIOSARCOMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 26, 2026 19:38 UTC
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Brain tumor tissue study could unlock new treatments
Knowledge-focused Recruiting nowThis study collects samples of glioblastoma (a type of brain tumor) and blood from 120 adults during standard surgery. Researchers will examine tissue from different parts of the same tumor to see how they differ. The goal is to learn more about the tumor's structure and behavior…
Matched conditions: GLIOSARCOMA
Sponsor: Baptist Health South Florida • Aim: Knowledge-focused
Last updated May 16, 2026 22:32 UTC