GLIOSARCOMA
Clinical trials for GLIOSARCOMA explained in plain language.
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New immunotherapy combo takes on deadliest brain cancer
Disease control CompletedThis study tested whether combining radiation with two immunotherapy drugs (ipilimumab and nivolumab) works better than the usual radiation plus chemotherapy (temozolomide) for a type of brain cancer called MGMT-unmethylated glioblastoma. About 159 newly diagnosed patients took p…
Matched conditions: GLIOSARCOMA
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Aggressive brain tumor trial combines three treatments to fight recurrence
Disease control CompletedThis study tested whether adding whole brain radiation and a drug called plerixafor to standard chemotherapy can help people with a newly diagnosed aggressive brain tumor (glioblastoma). Twenty-one adults took part. The goal was to see if the combination could delay tumor growth …
Matched conditions: GLIOSARCOMA
Phase: PHASE2 • Sponsor: Lawrence D Recht • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Immunotherapy combo shows promise in aggressive brain cancer trial
Disease control CompletedThis study tested whether adding the immunotherapy drug atezolizumab to standard chemotherapy and radiation helps people with newly diagnosed glioblastoma, a fast-growing brain cancer. The trial enrolled 60 patients and focused on safety and survival. While the treatment aims to …
Matched conditions: GLIOSARCOMA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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Second radiation blast shows promise for aggressive brain cancer
Disease control CompletedThis study looked at whether giving a second round of radiation is safe for people whose glioblastoma (a fast-growing brain tumor) has come back after standard treatment. Seventeen adults aged 18 to 50 with good overall health took part. The goal was to find the highest safe dose…
Matched conditions: GLIOSARCOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:48 UTC
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Blood tests may predict brain tumor treatment success
Knowledge-focused CompletedThis study looked at 47 adults with newly diagnosed glioblastoma or gliosarcoma to see if changes in immune cells in the blood could predict how well treatment works. Participants received a combination of immunotherapy drugs (ipilimumab and nivolumab) plus standard chemotherapy …
Matched conditions: GLIOSARCOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC