Supercharged immune cells take on deadly brain tumors

NCT ID NCT07579208

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tests a new approach for people with recurrent glioblastoma, an aggressive brain cancer that has come back after standard treatment. Researchers will give patients specially engineered natural killer (NK) cells, either directly into the brain or through an IV, to see which method is safer. The study involves 36 adults and focuses on side effects and the best way to deliver the cells.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
engineered natural killer (NK) cells
What this could lead to
If it works, this could point toward a new treatment option for recurrent glioblastoma, a brain cancer with few options.
What could go wrong
This is a very early Phase 1 trial with only 36 people. It is designed mainly to check safety, not yet to prove the treatment works. There may be side effects from the cells or the delivery method.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.