Ultrasound opens brain barrier to supercharge immune attack on deadly tumor

NCT ID NCT07343986

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests a new treatment for a fast-growing brain cancer called glioblastoma. It combines special immune cells (EGFR BATs) with low-intensity focused ultrasound to temporarily open the blood-brain barrier, allowing more treatment to reach the tumor. The study involves 12 adults with a specific type of glioblastoma that has not responded to standard therapy. The main goals are to check safety and see if the treatment can get into the brain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22903, United States

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