Ultrasound opens brain barrier to supercharged immune cells in aggressive cancer trial

NCT ID NCT07343986

First seen Jan 18, 2026 · Last updated May 07, 2026 · Updated 12 times

Summary

This early-phase trial tests a new treatment for a fast-growing brain cancer called glioblastoma. It combines a patient's own immune cells, trained to attack the cancer, with low-intensity ultrasound to temporarily open the blood-brain barrier. The goal is to see if this approach is safe and can get more immune cells into the brain to fight the tumor. The study involves 12 adults whose cancer has a specific genetic marker (MGMT unmethylated).

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Virginia

    RECRUITING

    Charlottesville, Virginia, 22903, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

Conditions

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