Can a seizure drug outsmart a deadly brain tumor?
NCT ID NCT07758062
First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time
Summary
This trial tests whether adding levetiracetam, a seizure medication, to the standard treatment for glioblastoma can improve outcomes. Glioblastoma is an aggressive brain cancer with poor survival despite current therapy. The study focuses on tumors with low oxygen levels, which are linked to treatment resistance. Participants receive either levetiracetam plus standard chemo-radiation or standard treatment alone, and researchers will compare how long patients live without the cancer progressing.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Levetiracetam extended-release granules added to the standard Stupp regimen (temozolomide plus radiotherapy)
- What this could lead to
- If it works, adding levetiracetam to standard treatment could slow tumor growth and extend survival for people with a hard-to-treat brain cancer.
- What could go wrong
- This is a phase 2 trial, so results are preliminary. The drug may not improve outcomes, and side effects could offset any benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tianjin Medical University General Hospital
Tianjin, Tianjin Municipality, 300052, China
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Other studies related to the condition(s) this trial covers.
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