New hope for advanced cervical cancer: Triple-Drug combo trial launches
NCT ID NCT07177716
First seen Jun 26, 2026 ยท Last updated Jun 26, 2026
Summary
This clinical trial is testing whether a combination of two immunotherapy drugs (LB1410 and LB4330) plus a targeted therapy (lenvatinib) can shrink tumors or slow disease progression in people with advanced cervical cancer that has returned or spread. The study will compare this new combo against standard chemotherapy chosen by the doctor. About 120 participants will be enrolled, and the main goals are to see how many patients respond and how long the response lasts.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- LB1410 (an immunotherapy drug) plus lenvatinib (a targeted therapy), with or without LB4330 (another immunotherapy drug)
- What this could lead to
- If it works, this could offer a new treatment option for people with advanced cervical cancer that has stopped responding to standard therapies.
- What could go wrong
- This is an early-to-mid stage trial with only 120 participants, so results may not apply to everyone. The combination of drugs may cause significant side effects, and there is no guarantee it will work better than existing chemotherapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fudan University Shanghai Cancer Center
Shanghai, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can robotic surgery match open surgery in beating cervical cancer?
- Blood test clues could sharpen cervical cancer treatment