New drug combo aims to boost cervical cancer survival
NCT ID NCT07649174
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase II trial tests whether adding the immunotherapy drug cadonilimab to chemotherapy before surgery helps people with locally advanced cervical cancer live longer without the disease coming back. About 134 participants will be randomly assigned to receive either the drug combo plus surgery or standard chemoradiotherapy. The main goal is to see if the new approach improves the two-year progression-free survival rate.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cadonilimab (an immunotherapy drug) plus chemotherapy
- What this could lead to
- If it works, this could offer a more effective treatment approach for locally advanced cervical cancer, potentially improving the chance of staying cancer-free after surgery.
- What could go wrong
- This is an early Phase II trial with only 134 participants, so results may not apply to everyone. Immunotherapy can cause side effects like immune reactions, and the combination may not prove better than standard chemoradiotherapy.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Obstetrics and Gynecology Hospital of Fudan University
Shanghai, 201101, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can an antiviral make radiation more effective against cervical cancer?
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- Can a Two-Antibody combo outsmart advanced cancer?
- Can robotic surgery match open surgery in beating cervical cancer?
- Blood test clues could sharpen cervical cancer treatment