CERVICAL CANCER

This study tested a new radioactive drug, [225Ac]-FPI-1434, in people with advanced solid tumors that had stopped responding to standard treatments. The goal was to check safety and find the right dose. The study was terminated early, so results are limited. It involved 78 partic…

This study tested a combination of two drugs, toripalimab (an immunotherapy) and chidamide (a targeted therapy), in women with advanced cervical cancer that had returned or spread. The goal was to see if the combination was safe and could shrink tumors. Only 5 women took part bef…

This study tested a new drug called OC-001, given alone or with an immunotherapy drug (Avelumab), in people with advanced cancers that had spread. The goal was to check safety and how the drug moves through the body. The study was stopped early and involved 73 participants with v…

This early-phase study tested a new drug called INCB099318 in 105 people with advanced solid tumors that had stopped responding to standard treatments. The main goal was to check the drug's safety and how the body processes it. The study was terminated early, so results are limit…

This trial tested a drug called tisotumab vedotin, alone or with other medicines, in 214 people with cervical cancer that had returned or spread. The goal was to find safe doses and see if tumors shrank. The study was stopped early, but the results help doctors understand how to …

This study tested whether adding weekly chemotherapy with carboplatin and paclitaxel after standard chemoradiation could help people with advanced cervical cancer that has spread to lymph nodes near the aorta. The trial enrolled 21 adults and aimed to see if this extra treatment …

This early-phase study tested a new drug called PHN-010 in 26 people with advanced solid tumors (lung, colon, endometrial, ovarian, or cervical cancer) that had already been treated with at least one prior therapy. The drug is an antibody-drug conjugate designed to deliver a toxi…

This early-stage study tested a new drug called SO-C101, either alone or with another drug (pembrolizumab), in 115 people with advanced solid tumors like lung, kidney, or skin cancer. The main goal was to check safety and find the right dose. The study was stopped early, so resul…

This study tested two experimental drugs (AGEN2034 alone or with AGEN1884) in 211 women with advanced cervical cancer that came back after standard chemotherapy. The goal was to see if the drugs could shrink tumors. The trial was terminated early, so results are limited. Particip…

This study tested whether connecting low-income patients with help for basic needs—like food, housing, and transportation—would help them attend a crucial follow-up appointment after an abnormal cervical cancer screening. It was a small trial that ended early. The goal was to see…

This study compared two methods of collecting tissue from the cervix (endocervical curettage) in women with abnormal Pap smears. The goal was to see if using a soft brush (cytobrush) causes less pain than the standard metal tool (Kevorkian curette) while still getting enough tiss…

This study aimed to see if DNA from cervical cancer tumors can be found in the blood of patients. Researchers wanted to know if this could help detect early signs of cancer spread. The study included 26 patients with cervical cancer and used blood samples to look for tumor DNA.