Gentler cervical screening tool tested, but study cut short

NCT ID NCT04000477

Terminated Symptom relief Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two devices used to collect tissue from the cervix during screening for cervical cancer: the standard Kevorkian curette and a softer cytobrush. The goal was to see if the cytobrush causes less pain while still getting enough cells for diagnosis. Only 3 women were enrolled before the study was stopped, so no firm conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cytobrush and Kevorkian curette (medical devices)
What this could lead to: If the cytobrush works as well as the curette but causes less pain, it could become a more comfortable option for cervical screening procedures.
What could go wrong: The trial was terminated early with only 3 participants, so results are very limited and may not be reliable. The cytobrush might also fail to collect enough tissue for diagnosis.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cervical cancer cervical intraepithelial neoplasia Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL CANCER PATHOLOGICAL SCREENING SMEAR

Contacts and locations

Locations

Service de gynécologie endocrinienne et médecine de la reproduction

Lille, France

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