Pee test could replace pap smear for some women

NCT ID NCT03598946

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether offering a home urine test for human papillomavirus (HPV) could encourage more women to get screened for cervical cancer. The trial targeted women aged 30–65 in Brittany, France, who had not responded to an initial invitation for a Pap smear. Participants received a kit to collect a urine sample at home and mail it to a lab. If the test was positive for high-risk HPV, they were urged to follow up with a doctor for a Pap smear. The study aimed to see if this at-home option would boost screening participation, especially among women from lower socioeconomic backgrounds. However, the trial was terminated early, so the full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
urinary test (home HPV urine test)
What this could lead to
If successful, this approach could offer a convenient, at-home screening option to reach women who avoid traditional Pap smears, potentially catching more cervical cancers early.
What could go wrong
The study was terminated early, so results are limited. Home urine tests may be less accurate than a clinic-based Pap smear, and the approach may not work equally well across all socioeconomic groups.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Christopher PAYAN

    Brest, France

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