New tracer injection could sharpen cancer detection in lymph nodes

NCT ID NCT02285192

Ongoing Diagnosis Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting a radioactive sugar tracer (18F-FDG) into the cervix before a PET/CT scan can better show which pelvic lymph nodes contain cancer in women with early-stage cervical or high-grade endometrial cancer. The goal is to improve surgical planning by more accurately mapping cancer spread. The trial involves 42 women and compares imaging results with lab analysis of removed lymph nodes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 18F-Fluorodeoxyglucose (18F-FDG)
What this could lead to: If successful, this could provide a more accurate way to map cancer spread to lymph nodes, helping surgeons remove the right nodes and potentially improving treatment planning.
What could go wrong: This is a small, early-phase study with only 42 participants, so results may not apply to all patients. The technique is still experimental and may not be more accurate than current methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cervical cancer cervical carcinoma endometrial cancer endometrial carcinoma endometrium neoplasm Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL CANCER ENDOMETRIAL CANCER

Contacts and locations

Locations

Memorial Sloan Kettering Basking Ridge (Consent only)

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (Consent only)

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States
Memorial Sloan Kettering Commack (Consent only)

Commack, New York, United States
Memorial Sloan Kettering Monmouth (Consent only)

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (Consent only)

Uniondale, New York, 11553, United States
Memorial Sloan Kettering Westchester (Consent only)

Harrison, New York, 10604, United States

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