Immunotherapy combo aims to stop cervical cancer in its tracks

NCT ID NCT07340489

First seen Jan 16, 2026 · Last updated Jun 22, 2026 · Updated 23 times

Summary

This phase II trial is testing whether adding the immunotherapy drug serplulimab to standard chemoradiotherapy can help people with locally advanced cervical cancer live longer without their disease getting worse. About 216 participants who have not yet been treated will receive either chemoradiotherapy alone or with serplulimab. The study will track how long it takes for the cancer to progress and monitor any side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tianjin Medical University Cancer Institute & Hospital,

    RECRUITING

    Tianjin, Tianjin Municipality, 300060, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

serplulimab (an immunotherapy drug) plus standard chemoradiotherapy (radiation and chemotherapy)

What this could lead to

If it works, this could lead to a new treatment option that helps keep cervical cancer from growing or coming back for longer.

What could go wrong

This is an early phase II trial with only 216 participants, so results may not apply to everyone. Immunotherapy can cause side effects like inflammation in healthy organs.

Conditions

The condition(s) this trial relates to.

cervical cancer Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.