Poop pills? stool transplants may ease immunotherapy side effects
NCT ID NCT04038619
First seen Jun 27, 2026 · Last updated Jul 16, 2026 · Updated 2 times
Summary
This early-stage trial tests whether a stool transplant (FMT) can help cancer patients who develop severe diarrhea or colon inflammation from immune-checkpoint inhibitor drugs. About 40 patients with various cancers will receive the transplant via colonoscopy. The main goal is to see if it is safe and can reduce gut symptoms within two weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fecal microbiota transplantation (stool transplant)
- What this could lead to
- If it works, this could offer a new way to manage severe diarrhea and colon inflammation caused by cancer immunotherapy, helping patients stay on their cancer treatment.
- What could go wrong
- This is a very early Phase 1 trial with only 40 participants, so it is not yet proven. The procedure involves a colonoscopy and carries risks like infection or worsening symptoms.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a radioactive tracer pinpoint Cancer's first stop?
- Can a simple CT scan catch lung cancer earlier in kuwait?
- Can a personalized exercise program boost recovery in cancer survivors?
- Could muscle loss predict blood cancer outcomes?
- Smartwatch could spot nerve damage before it starts
- Could ionized gas help fight breast cancer after surgery?