COLITIS
Clinical trials for COLITIS explained in plain language.
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New antibody combo trial aims to calm severe colitis without daily pills
Disease control Recruiting nowThis study tests whether long-acting antibodies, given alone or together, can safely reduce inflammation and improve symptoms in adults with moderate-to-severe ulcerative colitis. About 645 participants will receive the treatment through an IV infusion followed by regular shots. …
Matched conditions: COLITIS
Phase: PHASE2 • Sponsor: Spyre Therapeutics, Inc. • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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Poop pills may soothe Immunotherapy's gut side effects in cancer patients
Symptom relief Recruiting nowThis early-phase study tests whether fecal microbiota transplantation (FMT) can safely reduce severe diarrhea or colon inflammation caused by immune-checkpoint inhibitors in people with genitourinary and other cancers. About 40 participants will receive FMT and be monitored for s…
Matched conditions: COLITIS
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 16, 2026 22:32 UTC
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Poop pills could stop immunotherapy diarrhea
Symptom relief Recruiting nowThis study tests whether fecal microbiota transplantation (FMT) capsules can help people with diarrhea and colitis caused by immune checkpoint inhibitors, a common side effect of cancer treatment. Twenty adults with melanoma or kidney cancer will receive either FMT or placebo cap…
Matched conditions: COLITIS
Phase: NA • Sponsor: University of Aarhus • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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New pill aims to calm gut side effects from cancer drugs
Symptom relief Recruiting nowThis early-stage study tests a new medicine called KAN-004 in 21 adults who have diarrhea or colon inflammation from cancer immunotherapy. The main goal is to see if the drug is safe and tolerable. Participants must have a solid tumor treated with an immune checkpoint inhibitor a…
Matched conditions: COLITIS
Phase: PHASE1 • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Poop pills could soothe cancer drug side effects
Knowledge-focused Recruiting nowThis study looks at how the bacteria in your gut might cause stomach issues like diarrhea and colitis when you take certain cancer drugs called immune checkpoint inhibitors. Researchers will collect stool, blood, and tissue samples from 800 people with melanoma, lung, or genitour…
Matched conditions: COLITIS
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC