New drug duo targets Hard-to-Treat cancers
NCT ID NCT06795412
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called PYX-201 combined with pembrolizumab in people with advanced solid tumors that have not responded to other treatments. The goal is to find safe doses and see if the combination can shrink tumors. About 220 adults with certain cancers like head and neck, breast, or stomach cancer can join.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre Léon Bérard
RECRUITINGLyon, 69373, France
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Hopital Saint - Andre - CHU de Bordeaux
RECRUITINGBordeaux, 33075, France
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Hospital Clínico Universitario de Valencia
RECRUITINGValencia, 46010, Spain
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Hospital Universitario 12 de Octubre
RECRUITINGMadrid, 28041, Spain
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Hospital Universitario Ramón y Cajal
RECRUITINGMadrid, 28034, Spain
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Hospital Universitario Vall d'Hebron
RECRUITINGBarcelona, 08035, Spain
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Hôpital de la Timone
RECRUITINGMarseille, 13385, France
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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NEXT Oncology Houston
RECRUITINGHouston, Texas, 77054, United States
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NEXT Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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START Madrid - Hospital Universitario Fundación Jiménez Díaz
RECRUITINGMadrid, 28040, Spain
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Sarcoma Oncology Center
RECRUITINGSanta Monica, California, 90403, United States
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University of California San Diego
RECRUITINGSan Diego, California, 92093, United States
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University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Pittsburgh Medical Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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University of Texas - M.D. Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States