Could extra surgery boost survival in advanced cervical cancer?

NCT ID NCT05581121

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 27 times

Summary

This study looks at whether surgically removing lymph nodes near the aorta before standard chemoradiation helps people with stage IIIC1 cervical cancer live longer without the disease coming back. About 510 participants will be randomly assigned to either standard treatment or standard treatment plus the extra surgery. The goal is to see if the surgery leads to better outcomes over 5 years.

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Contacts and locations

Locations

  • CHRU Lille

    RECRUITING

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHRU Strasbourg - ICANS

    NOT_YET_RECRUITING

    Strasbourg, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Brest

    RECRUITING

    Brest, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Limoges

    RECRUITING

    Limoges, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Nîmes

    RECRUITING

    Nîmes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre François Baclesse

    NOT_YET_RECRUITING

    Caen, 14076, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Georges François Leclerc

    RECRUITING

    Dijon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Henri Becquerel

    WITHDRAWN

    Rouen, France

  • Centre Hospitalier Intercommunal de Créteil

    RECRUITING

    Créteil, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Universitaire La Reunion

    RECRUITING

    Saint-Pierre, 97448, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Léon Bérard

    RECRUITING

    Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Oscar Lambret

    RECRUITING

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chru Tours

    RECRUITING

    Tours, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • General UH in Prague - VFN

    RECRUITING

    Prague, 128 08, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • H. Clínico San Carlos / Madrid

    NOT_YET_RECRUITING

    Madrid, 28040, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • H.U. La Paz / Madrid

    RECRUITING

    Madrid, 28046, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Clinic i Provincial de Barcelona

    NOT_YET_RECRUITING

    Barcelona, 08036, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Cochin

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Européen Georges Pompidou

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Lariboisière Saint Louis

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Lyon Sud

    RECRUITING

    Pierre-Bénite, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Pitié-Salpêtrière

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • ICM Val d'Aurelle

    RECRUITING

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Bergonié

    RECRUITING

    Bordeaux, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Curie

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Curie Site - Saint Cloud

    NOT_YET_RECRUITING

    Saint-Cloud, 92210, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Godinot

    NOT_YET_RECRUITING

    Reims, 51726, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Universitaire du Cancer Toulouse - Oncopole

    RECRUITING

    Toulouse, 31059, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de Cancérologie de l'Ouest

    RECRUITING

    Angers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut de Cancérologie de l'Ouest

    RECRUITING

    Saint-Herblain, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Policlinico Universitario Agostino Gemelli

    NOT_YET_RECRUITING

    Roma, 00168, Italy

    Contact Email: •••••@•••••

  • UH Plzeň

    RECRUITING

    Pilsen, 326 00, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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