ADENOCARCINOMA

This study tests whether specially selected immune cells taken from a patient's own lung tumor can be grown in a lab and then given back to shrink advanced non-small cell lung cancer. About 85 adults aged 18–72 with stage IV or unresectable disease and a tumor that can be safely …

This study tests a new drug called relacorilant combined with two standard chemotherapy drugs for people with advanced pancreatic cancer that has spread. The goal is to see if the combination can help control the cancer longer and improve survival. About 60 participants will rece…

This study tests a new treatment using specially engineered natural killer (NK) cells that target a protein called TROP2 found on cancer cells. The cells are given directly into the abdomen to people with ovarian or pancreatic cancer that has stopped responding to standard treatm…

This study looks at whether surgically removing lymph nodes near the aorta before standard chemoradiation helps people with stage IIIC1 cervical cancer live longer without the disease coming back. About 510 participants will be randomly assigned to either standard treatment or st…

This study tests a powerful mix of treatments for people with advanced liver cancer that cannot be surgically removed. The approach combines tumor destruction (ablation), targeted therapy (lenvatinib), immunotherapy (tislelizumab), and a procedure that blocks the tumor's blood su…

This early-phase study tests a new combination of five chemotherapy drugs for people with advanced cancers of the upper digestive system, including pancreatic and stomach cancers. The goal is to find the safest dose based on a person's genetic makeup, which affects how the body p…

This early-stage study tests a new PET imaging agent, 18F-Clofarabine, to measure an enzyme (DCK) activity in metastatic cancers. The goal is to see if this scan can predict whether drugs like gemcitabine will be taken up by cancer cells. About 4 adults with metastatic cancer wil…

This study collects tumor samples and medical information from 1,500 people with pancreatic cancer. The goal is to build a large biobank that researchers can use to better understand the disease and develop new treatments. Participants do not receive any experimental therapy; the…

This study is following 3000 men with prostate cancer to understand why the disease progresses differently in different people. Researchers are looking at genetics, lifestyle, and medical history to find factors that predict recurrence or spread. The goal is to improve treatment …

This study aims to collect health information from 12,000 adults with lung or other chest cancers. Researchers want to understand why some people respond better to treatments than others, by looking at factors like genetics, lifestyle, and tumor details. The goal is to improve fu…