Could your own tumor cells beat lung cancer? new trial tests it
NCT ID NCT02133196
First seen Jun 24, 2026 · Last updated Aug 14, 2026 · Updated 3 times
Summary
This study takes white blood cells from a patient's lung tumor, grows them in large numbers in the lab, and gives them back to the patient to fight the cancer. The goal is to see if these specially selected cells can shrink tumors in people with advanced non-small cell lung cancer. Participants first undergo surgery to remove a tumor, then receive chemotherapy followed by the cell infusion and a drug called aldesleukin.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Young Tumor-Infiltrating Lymphocytes (TIL) plus chemotherapy and aldesleukin
- What this could lead to
- If it works, this could point toward a new treatment option for advanced non-small cell lung cancer that uses the patient's own immune cells to fight the tumor.
- What could go wrong
- This is an early phase II trial with only 85 participants, so results may not apply to everyone. The treatment involves strong chemotherapy and can cause serious side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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