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New combo aims to fix chemo side effect in cancer survivors

NCT ID NCT07586826

Recruiting now Disease control Sponsor: Peking University People's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for adults with certain cancers (like breast, lung, or ovarian) that are in complete remission but have persistently low platelet counts from past chemotherapy. It tests whether adding a vitamin A derivative (ATRA) to a standard platelet-boosting drug works better than the standard drug alone. About 220 participants will receive either the combination or the single drug for 12 weeks, and researchers will track platelet levels and safety.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm cervical cancer chemotherapy-induced toxicity endometrium neoplasm fallopian tube cancer fallopian tube neoplasm female reproductive organ cancer lung cancer lung neoplasm non-small cell lung carcinoma ovarian cancer Pathologic Complete Response primary peritoneal carcinoma thrombocytopenia Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER CERVICAL CANCER CHEMOTHERAPY-INDUCED THROMBOCYTOPENIA FALLOPIAN TUBE CANCER GYNECOLOGIC CANCERS LUNG CANCER NON-SMALL-CELL LUNG CANCER OVARIAN CANCER PERSISTENT ISOLATED CHEMOTHERAPY-INDUCED THROMBOCYTOPENIA PRIMARY PERITONEAL CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Peking University People's Hospital

    RECRUITING

    Beijing, 100044, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••