Peking University People's Hospital

This early-phase trial tests a new injection called IASO207 for people with relapsed or refractory B-cell blood cancers. Unlike current CAR-T therapies that require removing and engineering cells in a lab, IASO207 is designed to create cancer-fighting T cells directly inside the …

This trial tests whether a drug called coated aldehyde oxystarch (Xiqing) can reduce protein-bound uremic toxins in adults with end-stage renal disease who are on dialysis. Participants take the drug three times daily for three months. Researchers measure toxin levels in the bloo…

This observational study will follow 300 people with wet age-related macular degeneration (nAMD) who receive aflibercept 8 mg injections as part of their routine care. Researchers want to see how well the drug improves vision and reduces retinal swelling over 12 months, and what …

This study is testing a new treatment model for elderly patients (65+) with early-stage lung cancer. It combines advanced surgical techniques, personalized care before and after surgery, and rehabilitation programs. The goal is to improve survival and reduce complications. Resear…

This early-stage trial is testing a new type of CAR-T cell therapy, called CT0890B, for people with acute myeloid leukemia (AML) that has come back or not responded to treatment. The therapy uses donor-derived immune cells that are engineered to target a protein called NKG2DL on …

This study tests a new drug called Ivonescimab for people with non-small cell lung cancer who need surgery. The drug is given before surgery to shrink tumors and make them easier to remove. The study compares Ivonescimab to standard treatments and looks at how well it works and w…

This early study tests a new treatment called IASO207 for people with active lupus that hasn't responded to standard therapies. The treatment works by creating special immune cells inside the body to target and calm the overactive immune system. The study will check if it's safe …

This study is for people with a high-risk type of leukemia called CMML. It tests a stronger chemotherapy combination (including thiotepa) given before a stem cell transplant from a donor. The goal is to see if this approach helps patients live longer without the cancer coming bac…

This study tests whether adding all-trans retinoic acid to romiplostim N01 can better raise platelet counts in adults who have low platelets after finishing chemotherapy for gastrointestinal cancers. About 220 participants will receive either the combo or romiplostim alone for 12…

This study is for adults with certain cancers (like breast, lung, or ovarian) that are in complete remission but have persistently low platelet counts from past chemotherapy. It tests whether adding a vitamin A derivative (ATRA) to a standard platelet-boosting drug works better t…

This study tests a new type of CAR-T cell therapy that targets a protein called CD5 on cancer cells. It is for people with T-cell acute lymphoblastic leukemia or T-cell lymphoma that has come back or not responded to treatment. The trial has two phases: first, finding the safest …

This study is testing a drug called deucravacitinib in 10 adults with idiopathic inflammatory myopathies, a group of rare diseases that cause muscle inflammation and weakness. Participants will take one pill daily for 6 months. Researchers will track symptom changes and lab resul…

This study tests whether fucoidan, a substance from brown seaweed, can help adults with active rheumatoid arthritis who haven't improved enough on standard medications. The trial will enroll 40 people and follow them for 12 weeks to see if joint pain and swelling improve. Fucoida…

This study tests whether adding an extra step (a special blade to open drainage channels) to standard cataract-and-glaucoma surgery can better lower eye pressure in people with chronic angle-closure glaucoma and cataracts. About 68 adults will be randomly assigned to one of two s…

This study tests whether taking barley green supplements before meals can help reduce visceral fat (the harmful fat around your organs) in people with high body fat. Sixty-six participants will either receive barley green plus a calorie-controlled diet or just the diet alone. Res…

This study tests a new type of CAR T-cell therapy that uses nanobodies to target two proteins (CD19 and CD22) on leukemia cells. It is for people aged 12 to 65 whose B-cell acute lymphoblastic leukemia has come back or not responded to other treatments. The goal is to see if this…

This study tests a new minimally invasive treatment that freezes and then heats breast tumors, comparing it to standard breast-conserving surgery in 264 women with early-stage, hormone-positive breast cancer. The goal is to see if the ablation method can control the cancer just a…

This study tests a combination of two drugs, apatinib and liposomal irinotecan, in people with advanced osteosarcoma (bone cancer) that has spread or come back after standard treatments. The goal is to find the safest and most effective dose and see if the combo can shrink tumors…

This study is tracking 10,000 Chinese adults with rheumatoid arthritis who are starting or continuing a drug called subcutaneous methotrexate. Researchers want to see how well it works and how safe it is in everyday medical practice, including in patients with additional lung or …

This study compares two treatments for patients with B-cell acute lymphoblastic leukemia who still have small amounts of cancer cells (minimal residual disease) after a stem cell transplant. One group receives a single infusion of their own genetically modified immune cells (CAR-…

This study tests whether a blood test (ctDNA) can identify women with early-stage, hormone-positive breast cancer who can safely avoid chemotherapy. Instead of chemo, they receive a targeted pill (dalpiciclib) plus hormone therapy before surgery. The goal is to reduce side effect…

This early-phase trial is testing a new type of cell therapy that uses a patient's own immune cells, engineered to attack two targets (CD19 and CD20) on lymphoma cells. It aims to see if this approach is safe for people with aggressive B-cell lymphoma that has come back or not re…

This study tests whether hepatitis B immunoglobulin (HBIG) can help people with chronic hepatitis B stay virus-free after they've cleared the surface antigen (a key sign of cure). Researchers will give HBIG shots to 132 participants who already cleared the virus with standard the…

This study looks at whether specific diets can help overweight women with endometrial cancer who are receiving fertility-sparing therapy. Participants are randomly assigned to intermittent fasting, a low-energy balanced diet, or routine care. The goal is to see if these diets imp…

This early-stage trial tests a new treatment called CD7-targeted CAR-T cells for people with T-lymphoblastic leukemia or lymphoma that remains after a stem cell transplant. The therapy uses a patient's own or a donor's immune cells, modified to find and destroy cancer cells. The …

This study is testing a new device that first freezes and then heats breast tumors to destroy them. It is for patients who cannot have surgery due to health reasons or who choose not to. The goal is to see if this approach can control the cancer and prevent it from coming back, w…

This study tests a procedure where a person's own skin cells are transplanted onto stable white patches caused by vitiligo. The goal is to see how well and how safely it restores color over the long term. The trial will enroll 30 people with stable vitiligo who have not responded…

This study tests whether adding teriflunomide (a drug used for multiple sclerosis) to standard high-dose dexamethasone works better than dexamethasone alone for adults newly diagnosed with immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, caus…

This study tests whether a calorie-controlled diet can improve tumor outcomes and metabolic health in overweight or obese women with endometrial cancer who are undergoing fertility-sparing treatment. 240 participants will be randomly assigned to either a structured weight managem…

This study compares two ways to take tissue samples from stomach tumors to see which one gives a more accurate diagnosis. About 96 adults with stomach tumors at least 15mm in size will be randomly assigned to one of the two methods. The goal is to improve how doctors diagnose the…

This study is testing a new radioactive tracer called 68Ga-TOI-1 for PET scans in people with lung cancer or suspicious lung nodules. The tracer targets a protein (CDH3) found only on cancer cells, which may help doctors see tumors more clearly than current scans. About 80 partic…

This study tests a new radioactive tracer called [68Ga]Ga-PN-EpC1 for PET/CT scans in 30 people with suspected or confirmed epithelial tumors. The tracer targets a protein called EpCAM found on many cancer cells. Researchers want to see if it can find tumors more accurately than …

This study tests whether a special PET/CT scan (FAPI-PET/CT) and a fluorescent dye can better predict how well lung cancer responds to pre-surgery therapy and help surgeons see tumors during operation. 200 adults with stage II-IIIB non-small cell lung cancer will receive the scan…

This study is testing an artificial intelligence system that reads medical images like X-rays and MRIs to diagnose and stage osteoporosis and osteoarthritis. Researchers aim to make diagnosis more accurate and consistent. The trial will enroll 2,000 adults who have already had im…

This study uses artificial intelligence to look at CT scans that people already had for other reasons. The goal is to create a tool that can estimate bone age and catch early signs of osteoporosis without needing extra tests or radiation. Researchers will study 3,000 adults to se…

This study looks at whether the amount of light in the room changes how much anesthesia medicine people need during surgery. 66 adults having general anesthesia will be randomly assigned to wear an eye shield or not. Researchers will measure drug doses, time to fall asleep, and t…

This study tracks 6000 stem cell transplant patients over 5 years to understand serious fungal infections. Researchers will collect data on diagnosis, treatment, and survival to create better prevention and care guidelines. The goal is to improve long-term outcomes for transplant…

This observational study looks at whether leukemia stem cells can predict if acute myeloid leukemia (AML) with MLL rearrangement will come back. Researchers will measure these stem cells in bone marrow samples taken during regular check-ups. The goal is to improve relapse predict…

This study looks at how tiny fibers in the eye, called the vitreous zonule, might play a role in causing primary angle-closure glaucoma, a serious eye condition. Researchers will use advanced 3D ultrasound to take detailed pictures of these fibers in 440 adults, including those w…

This study is testing a new, highly sensitive blood test (digital PCR) to find tiny amounts of leukemia cells that remain after a stem cell transplant in people with acute myeloid leukemia (AML). The goal is to see if this test can predict a relapse earlier than current methods. …

This study looks at whether a rapid drop in a blood marker called dFLC can predict a complete response in people with AL amyloidosis treated with daratumumab-based therapy. Researchers will follow 50 patients to see if early changes in dFLC levels match up with later treatment su…

This study looks at whether advanced blood tests and artificial intelligence can help detect lung cancer recurrence earlier and without invasive procedures. About 100 adults who had surgery for stage IB-IIIA lung cancer and received standard chemo-immunotherapy before surgery wil…

This study looks at whether detecting MDS stem cells using a special lab test (flow cytometry) can predict if the disease will come back after a stem cell transplant. Researchers will follow 163 MDS patients for one year after transplant to see if this method is better than curre…

This large observational study will follow 10,000 people who have had a stem cell transplant to see how often they develop heart problems like heart attacks, stroke, or heart failure. Researchers will collect medical data over time to better understand who is at risk and why. The…

This study looks at whether detecting leftover leukemia stem cells in the blood or bone marrow after chemotherapy can better predict if a child's leukemia will come back. About 283 children with newly diagnosed acute myeloid leukemia will be followed. The goal is to improve relap…

This study will follow 500 Chinese patients newly diagnosed with multiple myeloma who are receiving immunotherapy as their first treatment. Researchers will collect data on which treatments are used and how well they work over one year, with longer follow-up for survival. The goa…

This study aims to create a prediction tool for pregnant women with aplastic anemia, a rare blood disorder that raises risks of bleeding, infection, and complications like preterm birth. Researchers will follow 300 women to identify factors that lead to poor outcomes for mother a…