Peking University People's Hospital

This study tests a new type of CAR-T cell therapy that uses nanobodies to target a protein called CD5 on cancer cells. It is for people aged 3 to 70 with T-cell acute lymphoblastic leukemia or T-cell lymphoma that has come back or not responded to other treatments. The goal is to…

This study tests a procedure where a person's own skin cells are transplanted onto white patches caused by vitiligo. The goal is to see how well and how long the color returns. The trial involves 30 people with stable vitiligo who have not responded to other treatments.

This study tests whether adding a vitamin A-like drug (ATRA) to a platelet-boosting medication (romiplostim N01) works better than the platelet drug alone for cancer survivors whose platelet counts stay low after chemotherapy. About 220 adults with gynecologic, breast, or lung ca…

This study follows 10,000 Chinese adults with rheumatoid arthritis who are starting or already using methotrexate injections. Researchers want to see how well the drug works and how safe it is in everyday medical practice, including in patients with additional lung or heart probl…

This study looks at adults whose platelet counts stayed low after finishing chemotherapy for gastrointestinal cancers (like stomach, pancreas, or colorectal). Participants get either a standard platelet-boosting drug alone or combined with another medicine (ATRA) for 12 weeks. Th…

This study tests a combination of two drugs, apatinib and liposomal irinotecan, in people with advanced osteosarcoma (bone cancer) that has spread or returned after standard treatments. About 56 participants will receive the drugs to find the best dose and see if the combination …

This early-phase study tests whether specially engineered immune cells (CAR-T cells) can eliminate small amounts of leftover T-cell leukemia or lymphoma in patients who have already received a stem cell transplant. About 18 participants will receive the treatment and be monitored…

This study looks at how different diets affect weight and cancer outcomes in overweight or obese women with endometrial cancer who are receiving fertility-sparing therapy. Participants are randomly assigned to intermittent fasting, a low-energy balanced diet, or routine self-mana…

This study tests whether adding teriflunomide to high-dose dexamethasone works better than dexamethasone alone for adults newly diagnosed with immune thrombocytopenia (ITP), a condition where the immune system destroys platelets, causing bleeding. About 132 participants will rece…

This study is testing a daily pill called deucravacitinib in 10 adults with active inflammatory muscle diseases (myositis) that haven't responded well to standard treatments. The goal is to see if the drug can reduce muscle inflammation and improve strength and daily function ove…

This study tests a new minimally invasive treatment that freezes and then heats breast tumors, comparing it to standard breast-conserving surgery. About 264 women aged 50+ with early-stage, hormone-positive breast cancer will be randomly assigned to one of the two treatments. The…

This study tests whether fucoidan, a substance from brown seaweed, can help people with active rheumatoid arthritis who haven't gotten better with usual medications. The trial will enroll 40 adults and follow them for 12 weeks to see if joint pain and swelling improve. Fucoidan w…

This study is for people with breast cancer who cannot have surgery due to health reasons or who choose not to for cosmetic concerns. It uses a special device that first freezes and then heats the tumor to destroy it. The goal is to see if this treatment is safe and effective at …

This early-phase study tests a new cell therapy that targets two proteins (CD19 and CD20) on lymphoma cells. It aims to see if this dual approach is safe and effective for people with aggressive B-cell lymphoma that has come back or not responded to prior treatments. The study wi…

This study looks at whether giving a shot of hepatitis B immunoglobulin (HBIG) after standard treatment can help people with chronic hepatitis B stay virus-free longer. About 132 adults who already cleared the virus with medication will either receive HBIG or no extra treatment. …

This study is for women with an early, hormone-sensitive type of breast cancer that has a higher chance of coming back. It tests whether a blood test (ctDNA) can identify who can safely skip chemotherapy and instead take a targeted pill (dalpiciclib) plus hormone therapy. About 3…

This study tests if adding a special blade procedure (KDB goniotomy) to standard cataract and glaucoma surgery helps lower eye pressure more effectively in people with chronic angle-closure glaucoma and cataracts. About 68 adults will be randomly assigned to one of two surgery gr…

This study looks at whether a supplement called barley green, when combined with a calorie-controlled diet, can reduce visceral fat (the harmful fat around your organs) in people with high body fat. Researchers will measure changes in fat area and explore how gut bacteria might p…

This study tests a new type of CAR T-cell therapy that uses tiny antibodies (nanobodies) to target two proteins, CD19 and CD22, on leukemia cells. It is for people aged 12 to 65 whose B-cell acute lymphoblastic leukemia has come back or stopped responding to other treatments. The…

This study looks at whether weight management can improve tumor outcomes and metabolism in overweight or obese women with endometrial cancer who are receiving fertility-sparing treatment. About 240 participants will be split into two groups: one gets weight management support, th…

This study is testing whether a personalized cell therapy (CAR-T) is better than standard chemotherapy at clearing tiny amounts of leftover leukemia cells in patients who have already had a stem cell transplant. The goal is to prevent the cancer from coming back. About 70 patient…

This study aims to create an artificial intelligence (AI) system that can automatically diagnose and stage osteoporosis and osteoarthritis from medical images like X-rays and MRIs. Researchers will enroll 2,000 adults to test if the AI can provide more consistent and accurate res…

This study tests a new radioactive tracer called [68Ga]Ga-PN-EpC1 that targets a protein (EpCAM) found on many epithelial tumors. About 30 adults with known or suspected epithelial tumors will receive the tracer and undergo a PET/CT scan before their planned biopsy or surgery. Th…

This study uses computer intelligence to analyze CT scans that people already had for other reasons, to check bone health and find early signs of osteoporosis. Researchers will look at scans from 3000 adults to see if the AI can accurately estimate bone age and weakness. The goal…

This study tests if a special PET scan (FAPI-PET) and a fluorescent dye can help doctors find leftover lung cancer during surgery after standard treatment. About 200 people with stage II-IIIB non-small cell lung cancer will get the scan and dye before and during surgery. The goal…

This study is testing a new type of PET scan that uses a special probe (68Ga-TOI-1) to target a protein called CDH3, which is only found on cancer cells. The goal is to see if this scan can more accurately detect and stage lung cancer compared to the standard PET scan. About 80 a…

This study looks at whether a rapid drop in a specific blood marker (dFLC) within the first week of treatment can predict a complete response in people with AL amyloidosis. About 50 participants will receive a standard daratumumab-based therapy. The goal is to see if early change…

This study compares two ways to take tissue samples from stomach tumors: a newer method called mucosal cutting biopsy (MCB) and a standard method called endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). The goal is to see which method gives a more accurate diagnosis.…

This study looks at how tiny fibers in the eye, called the vitreous zonule, may play a role in causing a type of glaucoma called primary angle-closure glaucoma. Researchers will use a special 3D ultrasound to take detailed pictures of these fibers in 440 people, including those w…

This study will follow about 500 Chinese adults newly diagnosed with multiple myeloma who are starting immunotherapy as their first treatment. Researchers will collect data on which drug combinations are used and how well they work over one year, with longer follow-up for surviva…

This study tracks 6,000 people who had a stem cell transplant to learn more about serious fungal infections that can occur afterward. Researchers will collect information on diagnosis, treatment, and outcomes over five years. The goal is to find better ways to prevent and treat t…

This study tests whether measuring certain stem cells in people with myelodysplastic syndromes (MDS) can better predict disease relapse after a stem cell transplant. Researchers will use a special blood test to track these cells before and after transplant in 163 patients. The go…

This study looks at whether finding leukemia stem cells in the blood and bone marrow can help predict if a child's leukemia will come back. It involves 283 children with acute myeloid leukemia. The goal is to improve relapse prediction so doctors can treat earlier and more effect…

This study follows 10,000 people who have had a stem cell transplant to see how often heart problems occur afterward. Researchers will collect medical information and track events like heart attacks, strokes, and heart failure. The goal is to better understand and manage these ri…

This observational study looks at whether leukemia stem cells can help predict if acute myeloid leukemia (AML) with MLL rearrangement will come back. Researchers will measure these stem cells in bone marrow samples taken during regular check-ups. The goal is to improve relapse pr…

This study looks at whether the amount of light in the operating room changes how much anesthesia medicine people need during surgery. 66 adults having general anesthesia will be randomly assigned to wear an eye shield or not. Researchers will measure drug doses, time to fall asl…

This study aims to create a prediction tool for pregnant women with aplastic anemia, a rare blood disorder that raises risks of bleeding, infection, and complications like preterm birth. Researchers will follow 300 women to identify factors that lead to poor outcomes for mother a…

This study looks at whether a highly sensitive blood test (digital PCR) can find tiny amounts of leukemia cells left after a stem cell transplant. Researchers will follow 100 patients with acute myeloid leukemia for 12 months after transplant, checking their blood at set times. T…

This study looks at whether advanced blood tests and artificial intelligence can detect lung cancer coming back after surgery, earlier than standard scans. Researchers will follow 100 people who had lung cancer surgery and chemotherapy. The goal is to create a better monitoring s…