Peking University People's Hospital

This study tests a new combination of drugs (BFCA regimen) given before a stem cell transplant from a half-matched donor. It aims to improve survival and reduce treatment failure in people aged 40 to 60 with severe aplastic anemia. The study will enroll 64 participants across mul…

This study looks at whether older or frail patients with acute myeloid leukemia (AML) can safely take a shorter course of the drug venetoclax, based on their bone marrow results on Day 14, instead of the standard longer course. About 250 participants will be randomly assigned to …

This study tests an experimental drug, golidocitinib, in 138 adults with primary immune thrombocytopenia (ITP) whose platelet counts remain low despite prior treatments. The study has two parts: first, finding a safe dose, then comparing the drug to a placebo in a blinded fashion…

This study tests different doses of zanubrutinib combined with high-dose dexamethasone in 60 adults newly diagnosed with immune thrombocytopenia (ITP), a condition causing low platelet counts and bleeding. The goal is to find the safest and most effective dose to raise platelet l…

This study will observe about 159 adults in China with a hard-to-treat type of multiple myeloma that has come back or not responded to other treatments. Researchers will track how well the drug elranatamab works in everyday medical practice, looking at tumor shrinkage, survival, …

This study compares two ways of giving donor immune cells (DLI) after a stem cell transplant to prevent cancer from coming back in people with hard-to-treat acute myeloid leukemia or myelodysplastic syndromes. About 200 participants will be randomly assigned to receive DLI either…

This study looks at whether a pill called ivarmacitinib can help people with moderate-to-severe eczema (atopic dermatitis) who didn't get better after using other injectable medications. About 300 adults will take the pill for 16 weeks, and doctors will check if their skin rash a…

This study tests the drug baricitinib in 28 adults who have dangerously low platelets that did not improve with standard treatments after a stem cell transplant. The goal is to see if baricitinib is safe and can help raise platelet counts without needing transfusions. Participant…

This study tests a new drug, Sonrotoclax, combined with steroids and possibly another drug (daratumumab) in 39 adults with a rare disease called AL amyloidosis who have a specific genetic marker (t(11;14)). The goal is to see if this treatment can reduce harmful protein buildup a…

This study tests a personalized approach for women with hormone receptor-positive, HER2-negative early breast cancer. Doctors use a blood test (ctDNA) to see if the cancer responds to a combination of targeted pills (CDK4/6 inhibitors) and hormone therapy before surgery. If the b…

This study tests whether the drug interferon-α can help prevent cancer from coming back in people with a specific genetic mutation (TP53) in acute myeloid leukemia or myelodysplastic syndromes. All participants have already had a stem cell transplant and show no signs of cancer. …

This early study tests an injection called IASO207 in 18 adults with B-cell blood cancers (like lymphoma) that returned or didn't respond to prior treatments. The main goals are to check safety and find the right dose, while also seeing if tumors shrink. It's a first step to see …

This study tests a non-invasive breathing therapy (oscillation and lung expansion guided by electrical impedance tomography) in 80 adults with severe blunt chest trauma who are on a breathing machine. The goal is to see if it improves lung function, shortens time on the ventilato…

This study looks at whether a new blood test (mNGS) can accurately find fungal lung infections in 1,000 people with blood disorders. Participants will give a blood sample and be followed for 42 days. The goal is to see if this test works better than current methods to help doctor…

This study aims to see if the position a woman gives birth in affects her risk of developing stress urinary incontinence after having a baby. Researchers will follow 669 first-time mothers, grouping them by whether they deliver lying on their back, upright, or on their side. They…

This study tests whether acupuncture can safely reduce hot flashes in women with hormone receptor-positive breast cancer who are on hormone therapy. Sixty participants will receive either real or sham acupuncture three times a week for eight weeks, then be followed for 16 more we…

This study will use a high-tech blood test (mass spectrometry) to look at different immune cells in 500 people with various autoimmune diseases and healthy volunteers. The goal is to find patterns that could help doctors screen for and diagnose these conditions earlier. No new tr…

This study will use the FreeStyle Libre 2 continuous glucose monitor to track blood sugar patterns in 120 people with rare forms of diabetes, such as monogenic diabetes and hyperinsulinemia. By comparing these patterns with existing data from healthy people and those with type 2 …

This study looks at how low body temperature during lung cancer surgery (using a tiny camera) affects pain and complications after the operation. About 144 people having this surgery will be watched closely. The goal is to understand if staying warm during surgery can lead to bet…

This study will follow 15 people with primary antibody immunodeficiency who are receiving immunoglobulin therapy. Researchers will measure changes in specific immune cells (T and B cells) in the blood and track how many infections participants get over time. The goal is to better…

This study will follow 4,000 patients who become critically ill after a stem cell transplant and need intensive care. Researchers will collect information on their health, treatments, and survival. The goal is to learn more about what happens to these patients to help improve car…

This observational study looks at how a protein called irisin, released during exercise, might protect the brain and lower the risk of confusion after surgery in people 65 and older. Researchers will measure irisin in spinal fluid and track delirium for five days after surgery. T…

This study looks at people with a type of glaucoma who need a combined cataract and glaucoma surgery. The goal is to find out which patients are most likely to develop a rare but serious complication called ciliary block, where fluid builds up in the wrong part of the eye. Resear…