Exercise hormone irisin may shield elderly brains from Post-Surgery confusion

NCT ID NCT07424170

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This observational study looks at how a protein called irisin, released during exercise, might protect the brain and lower the risk of postoperative delirium in older adults. Researchers will enroll 140 people aged 65 and older who are having non-cardiac surgery under spinal anesthesia. They will measure irisin levels in spinal fluid and track delirium for five days after surgery to see if daily activity and irisin are linked to better brain outcomes.

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Conditions

The condition(s) this trial relates to.

Emergence Delirium Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.