A common antioxidant may help platelets recover faster after stem cell transplant

NCT ID NCT07737262

Not yet recruiting Disease control Sponsor: Peking University People's Hospital Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This trial tests whether the antioxidant N-acetylcysteine (NAC) can help platelets recover faster after a stem cell transplant in people with severe aplastic anemia. Participants take NAC capsules three times daily from two weeks before transplant until two months after. The study compares platelet recovery rates between those who get NAC and those who do not.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: N-acetylcysteine (NAC) capsules taken by mouth
What this could lead to: If NAC works, it could speed platelet recovery after stem cell transplant, reducing bleeding risk and transfusion needs for patients with severe aplastic anemia.
What could go wrong: This is an early-phase trial with 142 participants, so results may not apply broadly. NAC can cause side effects like nausea or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aplastic anemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APLASTIC ANEMIA

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