Less oxygen during lung surgery may prevent collapse — a trial investigates
NCT ID NCT07721558
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This trial tests whether using 50% oxygen instead of 100% oxygen during one-lung ventilation reduces collapse (atelectasis) in the non-operated lung after thoracoscopic right lung lobectomy. One hundred adults undergoing elective surgery will be randomly assigned to receive either low or high oxygen levels, combined with individualized ventilation settings. The main outcome is the amount of lung collapse seen on CT scans about an hour after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- low inspired oxygen concentration (50% FiO₂) during one-lung ventilation
- What this could lead to
- If using less oxygen during surgery reduces lung collapse, it could improve recovery and lower complication rates for patients undergoing lung resection.
- What could go wrong
- This is a small, early-phase trial with only 100 patients, so results may not apply broadly. Lower oxygen levels also carry a risk of insufficient oxygenation during surgery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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