Two quick tests could flag Who's at risk of blood pressure drops during anesthesia

NCT ID NCT07766967

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This study looks at whether two simple bedside tests—the Passive Leg Raising (PLR) test and the Pleth Variability Index (PVI)—can predict a temporary drop in blood pressure that sometimes happens during a lung-opening procedure called an Alveolar Recruitment Maneuver (ARM). ARM is used during general anesthesia to prevent lung collapse and improve oxygen levels, but it can cause hypotension in some patients. The study will enroll 70 adults having elective non-cardiac, non-thoracic surgery under general anesthesia. Before each ARM, the PLR test and PVI will be measured to see if they can identify who is at risk, potentially allowing doctors to take preventive steps and make the procedure safer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Passive Leg Raising (PLR) test and Pleth Variability Index (PVI) as predictive tools
What this could lead to
If these tests work, doctors could identify at-risk patients before a lung-opening maneuver, preventing dangerous blood pressure drops during surgery.
What could go wrong
This is a small observational study, so results may not apply to all patients. The tests might not reliably predict hypotension, and the study does not test a treatment.

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Conditions

The condition(s) this trial relates to.

hypotensive disorder Pulmonary Atelectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Balıkesir Atatürk City Hospital

    Balıkesir, Altıeylül, 10100, Turkey (Türkiye)

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