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Smarter ventilator settings could ease breathing for ICU patients

NCT ID NCT07769307

NEW Not yet recruiting Disease control Sponsor: Capital Medical University Source: ClinicalTrials.gov ↗

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This pilot trial tests whether using a flow index—a simple measurement from the ventilator—to adjust pressure support can better match breathing effort in adult ICU patients who need a ventilator for more than 48 hours. Half the participants will have ventilator support adjusted using this new method, while the other half receives standard adjustments based on tidal volume and breathing rate. The goal is to see if the new method keeps respiratory muscle pressure in a healthy range, potentially reducing strain and improving recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Flow index-guided pressure support titration, a procedure that adjusts ventilator support based on a non-invasive flow index measurement.
What this could lead to
If successful, this could lead to a more precise way to set ventilator support, potentially reducing breathing effort and improving outcomes for ICU patients.
What could go wrong
This is a small pilot study, so results may not be conclusive. The approach may not prove safer or more effective than standard care, and there are risks of respiratory distress or other complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MECHANICAL VENTILATION

Contacts and locations

Locations

  • Capital Medical University Beijing Tiantan Hospital

    Beijing, Beijing Municipality, 100070, China

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