Capital Medical University

This early-stage study tests whether a drug called anisodine hydrobromide is safe for people having a stroke caused by a blocked large artery in the brain. About 92 adults aged 18 to 80 who are already scheduled for a clot-removal procedure will receive the drug. The main goal is…

This study tests whether using a real-time lung imaging tool (EIT) to guide breathing therapy helps people who have been on a breathing machine for a long time. The goal is to see if this personalized approach helps them breathe on their own sooner compared to standard therapy. T…

This phase 3 trial tests whether adding tocilizumab, an anti-inflammatory drug, to standard emergency stroke treatment improves outcomes for people with a severe stroke in the back of the brain. About 348 adults will receive either tocilizumab or a placebo by IV right before a pr…

This study tests whether giving the protein albumin (given as an IV drip for four days) along with standard clot-removal treatment helps people recover better after a severe stroke caused by a large blockage. About 1,200 adults aged 18-80 with anterior circulation strokes will be…

This study tests a new therapy called oscillation and lung expansion (OLE) in 60 adults on ventilators who have collapsed lungs (atelectasis). OLE combines continuous pressure, high-frequency vibrations, and medication mist to clear mucus and reopen lung tissue. Researchers will …

This study looks at the best time to start blood thinners in people with atrial fibrillation who had a stroke and emergency treatment to open a blocked artery. About 438 participants will be randomly assigned to start blood thinners within 4 days or between 5-14 days after the st…

This study looks at the best time to start blood thinners in people with atrial fibrillation who had a stroke and then emergency treatment to remove a clot. Some patients develop bleeding in the brain after the procedure, and doctors want to know if starting blood thinners early …

This study tests whether telemedicine support can improve stroke care in basic-level hospitals with limited resources. About 2,400 patients with acute ischemic stroke will be treated at hospitals that either receive round-the-clock remote guidance from expert stroke teams or do n…

This study tests a new method for setting ventilator support in ICU patients with acute hypoxic respiratory failure. Instead of using traditional targets like breath size and rate, the new approach adjusts support based on how hard the patient is breathing. The goal is to see if …

This study tests whether giving aspirin within 3 hours of clot-busting treatment for stroke can improve recovery without causing dangerous bleeding. About 1,184 adults who had an ischemic stroke will receive either aspirin or a placebo. The goal is to see if early aspirin leads t…

This study tests whether giving patients 100% oxygen (normobaric hyperoxia) before a clot-removal procedure can improve their recovery three months after a severe stroke. About 1,500 adults with acute ischemic stroke will be randomly assigned to receive either the extra oxygen or…

This study tests whether a noninvasive arm cuff therapy, called remote ischemic conditioning, can improve recovery in people who have had a major stroke and undergone a clot-removal procedure. The therapy involves briefly inflating and deflating a cuff on the upper arm to protect…

This study tests a new way to deliver radiation therapy for people with stage III lung cancer that cannot be removed by surgery. The treatment is personalized based on each patient's tumor sensitivity to radiation. The goal is to see if this approach helps people live longer and …

This study tests increasing doses of the clot-busting drug urokinase in 24 people with acute ischemic stroke, given within 6 hours of symptoms. The goal is to find the highest safe dose and develop a weight-based dosing plan. Researchers will watch closely for bleeding complicati…

This study aims to find early warning signs of Alzheimer's disease by analyzing body fluids, genes, and brain images in 6,000 older adults in China. Researchers hope to create a diagnostic kit and a risk prediction model that can identify the disease years before symptoms appear.…

This study aims to find the best cutoff values for key Alzheimer's-related proteins in spinal fluid and blood to improve diagnostic accuracy. Researchers will compare results from Alzheimer's patients, those with mild memory problems, people with other dementias, and healthy olde…

This study is testing a new blood test called the AD-seeds-detector that looks for specific protein clumps linked to Alzheimer's disease. Researchers will compare the test results from 1,500 people aged 55-75, including those with Alzheimer's, other dementias, and healthy individ…

This study tests whether a speaking valve combined with a pressure measurement can predict if the upper airway is open in people with a long-term tracheostomy. 300 participants will wear the valve for 30 minutes while pressure is measured, then undergo a bronchoscopy for comparis…

This study tests whether two antiviral drugs—suraxavir marboxil and oseltamivir (Tamiflu)—can prevent flu from spreading to uninfected roommates of flu patients in hospitals. About 384 people will take one of the drugs or a placebo for 5 days. Researchers will track how many get …

This study tests whether a precise type of radiation, called stereotactic radiotherapy, can safely reduce symptoms in people with treatment-resistant depression. Nine adults aged 18 to 50 who have not improved after at least two antidepressant trials will receive the treatment. R…

This study is observing tiny energy-producing parts of cells, called mitochondria, in the spinal fluid of people who have had a stroke or have Alzheimer's disease. Researchers want to see if these markers relate to how well patients recover after a stroke. The study does not give…

This study tests whether an AI tool called Xuanwu-NeuroAid 2.0 can help emergency room doctors better diagnose and treat patients with sudden brain or nerve problems. About 1,360 adults with acute neurological symptoms will be randomly assigned to receive either standard care or …

This study is following 3000 people in China who have cerebral venous thrombosis, a rare type of blood clot in the brain. Researchers will collect blood and spinal fluid samples to learn more about the disease and find markers that could help with diagnosis. The goal is to better…

This study is following 100,000 people in China over many years to learn more about dementia and memory loss. Researchers will track who develops these conditions, look for risk factors like genes and lifestyle, and find better ways to diagnose and prevent dementia. The goal is t…

This study is following 40,000 people from families with a strong history of Alzheimer's disease in China. Researchers are collecting genetic, brain imaging, and thinking and memory test data to learn how the disease develops over time. The goal is to find early signs of the dise…

This study involves 100 adults with long-term tracheostomy who are ready to have their tube removed. Researchers will compare three breathing tests done before removal to see which one best predicts a safe outcome. Lung function will also be measured five days after the tube is t…

This study follows 1,300 people who had a stroke or mini-stroke and completed a 1-year exercise program. Researchers will track them for 3 more years to see if the exercise helped prevent future strokes or improve daily function. No new treatments are given—this is purely observa…

This study aims to uncover the clinical features and molecular mechanisms behind obstructive sleep apnea (OSA). Researchers will analyze blood, saliva, and urine samples from 500 participants to build a multi-omics database. The goal is to identify biomarkers and treatment target…