New combo therapy aims to reopen collapsed lungs in ventilator patients
NCT ID NCT07451405
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new therapy called oscillation and lung expansion (OLE) in 60 adults on ventilators who have collapsed lungs (atelectasis). OLE combines continuous pressure, high-frequency vibrations, and medication mist to clear mucus and reopen lung tissue. Researchers will compare it to standard chest wall vibration therapy using CT scans and electrical impedance tomography to see which works better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oscillation and lung expansion (OLE) therapy
What this could lead to
If successful, this could provide a more effective and comfortable way to treat lung collapse in patients on ventilators, potentially reducing complications.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to all patients. The therapy may not work better than current methods and could cause discomfort or injury.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Respiratory rehabilitation center
RECRUITINGBeijing, Beijing Municipality, 100144, China
Contact Phone: •••-•••-••••
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Shuo Chen
COMPLETEDBeijing, China