When to thin the blood after a stroke? new trial seeks answer

NCT ID NCT07139301

First seen Jun 25, 2026 · Last updated Aug 06, 2026 · Updated 3 times

Summary

This study looks at the best time to start blood thinners in people with atrial fibrillation who had a stroke and emergency treatment to open a blocked artery. About 438 participants will be randomly assigned to start blood thinners within 4 days or between 5-14 days after the stroke. The goal is to see which timing better prevents another stroke, major bleeding, or death.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
direct oral anticoagulants (blood thinners)
What this could lead to
If it works, this could help doctors know the safest time to start blood thinners after a stroke, reducing the risk of another stroke or bleeding.
What could go wrong
This is a mid-sized trial, and results may not apply to all patients. Starting blood thinners too early could cause bleeding in the brain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aviation General Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

  • Baoding Sixth Hospital

    RECRUITING

    Baoding, Hebei, China

  • Beijing Shijingshan Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

  • Daliuta Experimental District People's Hospital of Shenmu City

    RECRUITING

    Shenmu, China

  • Fangcheng County People's Hospital

    RECRUITING

    Nanyang, Henan, China

  • Feicheng Hospital Of Shandong Yiyang Health Group

    RECRUITING

    Feicheng, Shandong, China

  • First Affiliated Hospital of Henan Polytechnic University

    RECRUITING

    Jiaozuo, China

  • Guoluo Prefecture People's Hospital

    RECRUITING

    Guoluo, China

  • Guoyao Northern Hospital (Baotou)

    RECRUITING

    Baotou, Shanxi, China

  • Heyuan People's Hospital

    RECRUITING

    Heyuan, Guangdong, China

  • Huanghua Municipal People's Hospital

    RECRUITING

    Huanghua, China

  • Jinan Zhangqiu District People's Hospital

    RECRUITING

    Jinan, Shandong, China

  • Laizhou City People's Hospital

    RECRUITING

    Laizhou, Shandong, China

  • Liaocheng Neurological Hospital

    RECRUITING

    Liaocheng, Shandong, China

  • Linshu County People's Hospital

    RECRUITING

    Xiazhuang, Shandong, China

  • Linyi People's Hospital

    RECRUITING

    Linyi, Shandong, China

  • Lushan County People's Hospital

    RECRUITING

    Pingdingshan, Henan, China

  • Ma'anshan People's Hospital

    RECRUITING

    Ma’anshan, Anhui, China

  • Nanyang Central Hospital

    RECRUITING

    Nanyang, Henan, China

  • Ningjin County People's Hospital

    RECRUITING

    Ningjin, China

  • Northern Jiangsu People's Hospital

    RECRUITING

    Yangzhou, Jiangsu, China

  • Ordos Central Hospital

    RECRUITING

    Ordos, Neimenggu, China

  • Qilu Hospital of Shandong University

    RECRUITING

    Jinan, China

  • Qinzhou First People's Hospital

    RECRUITING

    Qinzhou, Guangxi, China

  • Queshan County People's Hospital

    RECRUITING

    Zhumadian, Henan, China

  • Ren Shou County People's Hospital

    RECRUITING

    Renshou, China

  • ShanXi Cardiovascular Hospital

    RECRUITING

    Taiyuan, Shanxi, China

  • The Affiliated Hospital of Xuzhou Medical University

    RECRUITING

    Xuzhou, China

  • The First Affiliated Hospital of Harbin Medical University

    RECRUITING

    Harbin, Heilongjiang, China

  • The First Affiliated Hospital of Suzhou University

    RECRUITING

    Suzhou, Jiangsu, China

  • The Hongda Hospital of Jiamusi University

    RECRUITING

    Jiamusi, Heilongjiang, China

  • The People's Hospital of Yueqing

    RECRUITING

    Yueqing, Zhejiang, China

  • The Second Affiliated Hospital of Kunming Medical University

    RECRUITING

    Kunming, Yunnan, China

  • Tianyou Hospital, Wuhan University of Science and Technology

    RECRUITING

    Wuhan, Hubei, China

  • Xinyang Central Hospital

    RECRUITING

    Xinyang, Henan, China

  • Xiuyan Central Hospital

    RECRUITING

    Xiuyan, China

  • Xuanwu Hospital, Beijing, Beijing 100053

    RECRUITING

    Beijing, China

  • Yantai Yeda Hospital

    RECRUITING

    Yantai, Shandong, China

  • Yingkou Central Hospital

    RECRUITING

    Yingkou, Liaoning, China

  • Zhangzhou Municipal Hospital of Fujian Province

    RECRUITING

    Zhangzhou, Fujian, China

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